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AB69443

Anti-Unc93a antibody

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(2 제품이 사용된 논문 )

Rabbit Polyclonal Unc93a antibody. Suitable for WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human Protein unc-93 homolog A.
1 이미지
Western blot - Anti-Unc93a antibody (AB69443)
  • WB

Unknown

Western blot - Anti-Unc93a antibody (AB69443)

Lane 1:

Western blot - Anti-Unc93a antibody (ab69443) at 0.5 µg/mL

Lane 2:

Western blot - Anti-Unc93a antibody (ab69443) at 1 µg/mL

All lanes:

HeLa cell lysate at 15 µg

Predicted band size: 50 kDa

Observed band size: 48 kDa

false

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Synthetic Peptide within Human Protein unc-93 homolog A. The exact immunogen used to generate this antibody is proprietary information.

Q86WB7

Specificity

ab69443 will not cross-react with Unc93b.

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보완 제품

Primary Antibodies

AB134317

Anti-ANK-3 antibody [N106/20]

Immunocytochemistry/ Immunofluorescence - Anti-ANK-3 antibody [N106/20] (AB134317)

  • 1
  • 1
Primary Antibodies

AB205302

Anti-ATHL1 antibody [EPR13421]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-ATHL1 antibody [EPR13421] (AB205302)

  • 0
  • 0
Primary Antibodies

AB168133

Anti-DCC1 antibody

Immunocytochemistry/ Immunofluorescence - Anti-DCC1 antibody (AB168133)

  • 3
  • 1
Primary Antibodies

AB95198

Anti-Mup1 antibody

Western blot - Anti-Mup1 antibody (AB95198)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-1 µg/mL", "WB-species-notes": "<p></p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
보관 버퍼
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

The Unc93a protein sometimes referred to as Unc-93 Homolog A plays an important role in cellular processes. It is a protein with a molecular mass of approximately 67 kDa. Unc93a expresses mainly in various tissues suggesting its involvement in multiple physiological functions across different organ systems. It has been identified in the endoplasmic reticulum where it participates in unfolding protein response.
Biological function summary

Unc93a facilitates various essential cellular activities by acting as a part of a larger protein complex. Its primary role involves the regulation of immune responses and the proper functioning of immune cell signaling. The protein is important for maintaining the stability and function of membrane-associated proteins involved in these pathways. Unc93a contributes to the healthy communication within immune cells by modulating how they react to external signals.

Pathways

The Unc93a protein is integral to the immune response signaling pathways such as TLR (Toll-like receptor) signaling. It works closely with other proteins like MyD88 and TRIF which are essential mediators of signal transduction in this pathway. These interactions allow Unc93a to modulate the body’s response to pathogens ensuring effective immune defense mechanisms are in place.

Unc93a plays a significant role in autoimmune diseases such as systemic lupus erythematosus and inflammatory conditions like Crohn's disease. It links to these conditions through its interaction with proteins like TLR7 and TLR9 which are components of the immune response pathways. Dysregulation of Unc93a can lead to inappropriate immune responses contributing to the pathology of these diseases.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

See full target information Protein unc-93 homolog A

대체 명칭 보기

Protein unc-93 homolog A, HmUnc-93A, Unc-93A, UNC93A
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제품이 사용된 논문 (2)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Frontiers in cell and developmental biology 8:579 PubMed32733888

2020

Glucose Availability Alters Gene and Protein Expression of Several Newly Classified and Putative Solute Carriers in Mice Cortex Cell Culture and .

Applications

Unspecified application

Species

Unspecified reactive species

Mikaela M Ceder,Emilia Lekholm,Axel Klaesson,Rekha Tripathi,Nadine Schweizer,Lydia Weldai,Sourabh Patil,Robert Fredriksson

Frontiers in molecular neuroscience 10:351 PubMed29163028

2017

The Neuronal and Peripheral Expressed Membrane-Bound UNC93A Respond to Nutrient Availability in Mice.

Applications

Unspecified application

Species

Unspecified reactive species

Mikaela M Ceder,Emilia Lekholm,Sofie V Hellsten,Emelie Perland,Robert Fredriksson
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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