JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB234867

Anti-Use1 antibody

Be the first to review this product! 리뷰 제출

|

(1 출판물)

Rabbit Polyclonal USE1 antibody. Suitable for IP, WB, ICC/IF and reacts with Human, Mouse samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human USE1 aa 1-150.

대체 명칭 보기

USE1L, MDS032, USE1, Vesicle transport protein USE1, Putative MAPK-activating protein PM26, USE1-like protein, p31

1 이미지
Immunocytochemistry/ Immunofluorescence - Anti-Use1 antibody (AB234867)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-Use1 antibody (AB234867)

U-251 MG (human brain glioma cell line) cells stained for Use1 (green) using ab234867 at 1/100 dilution in ICC/IF, followed by Alexa Fluor 488® conjugated Goat Anti-Rabbit IgG (H+L).

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

IP, WB, ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human USE1 aa 1-150. The exact immunogen used to generate this antibody is proprietary information.

Q9NZ43

style
left-column

대체품

Primary Antibodies

AB111690

Anti-Use1 antibody

Immunocytochemistry/ Immunofluorescence - Anti-Use1 antibody (AB111690)

  • 0
  • 0

보완 제품

Primary Antibodies

AB234876

Anti-LRRTM4 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LRRTM4 antibody (AB234876)

  • 0
  • 0
Primary Antibodies

AB235037

Anti-HIC1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HIC1 antibody (AB235037)

  • 0
  • 0
Proteins & Peptides

AB156344

Recombinant Human Use1 protein (His tag N-Terminus)

SDS-PAGE - Recombinant Human Use1 protein (His tag N-Terminus) (AB156344)

  • 0
  • 0
Primary Antibodies

AB80864

Anti-Giantin antibody - Golgi Marker

BOND RX™ Validated|KO Validated|Lab Essentials

Immunocytochemistry/ Immunofluorescence - Anti-Giantin antibody - Golgi Marker (AB80864)

  • 4
  • 2
style
left-column

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "1/200 - 1/2000", "IP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/5000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/50 - 1/500", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/5000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
style
left-column
style
left-column

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein G
Purification 관련 사항
Purity >95%.
보관 버퍼
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
style
left-column

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Use1 also known as UNS-1 or Protein Transport Protein Use1 is involved in the SNARE-mediated transport mechanism. It has a molecular mass of approximately 29 kDa. This protein is expressed in various tissues with significant presence in the endoplasmic reticulum and Golgi apparatus. Structurally Use1 interacts with other SNARE proteins to regulate vesicle fusion processes essential for intracellular transport.
Biological function summary

Use1 plays an important role in the delivery and sorting of proteins within cells. It functions as a part of the SNARE complex which is important for the fusion of vesicles with target membranes. By ensuring the precise docking and release of vesicles this protein aids in maintaining proper cellular function. The SNARE complex including partners like Syntaxin 18 and BNIP1 ensures coordinated intracellular trafficking which is vital for cellular homeostasis.

Pathways

Use1 is deeply involved in the vesicular transport and cellular trafficking pathways. These pathways are essential for the movement of proteins and lipids between different organelles. Use1 works closely with the Golgi and endoplasmic reticulum trafficking pathways. It interacts with proteins such as Sec22b and Syntaxin 18 to facilitate vesicular transport processes. This activity ensures correct delivery of molecular cargos aiding in cellular function regulation and signal transduction.

Mutations or dysfunction of Use1 have been associated with neurodegenerative diseases and certain metabolic disorders. Neurodegenerative conditions like Alzheimer's disease show disrupted protein transport implicating Use1's role in proper neuronal function. Additionally Use1 connects with proteins like Syntaxin 5 highlighting its involvement in metabolic pathways that when altered may lead to disorders. Research continues to investigate Use1 as a potential therapeutic target for these conditions.
style
left-column
style
left-column

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

타겟 정보

SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.
See full target information USE1
style
left-column

제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Cellular and molecular biology (Noisy-le-Grand, France) 70:78-84 PubMed38836678

2024

M2 macrophages regulate KDM6B/PFKFB2 metabolic reprogramming of cervical squamous cell carcinoma through CXCL1.

Applications

Unspecified application

Species

Unspecified reactive species

Jing Yu,Longzhang Huang,Lihua Cao
제품이 사용된 논문 모두 보기
style
left-column
style
left-column
style
right-column

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com