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AB89829

Anti-VASP antibody

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(1 출판물)

Mouse Polyclonal VASP antibody. Carrier free. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human VASP.
2 이미지
Immunocytochemistry/ Immunofluorescence - Anti-VASP antibody (AB89829)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-VASP antibody (AB89829)

ab89829 at 10 μg/ml staining VASP in paraformaldehyde fixed, permeabilised HeLa cells by immunofluorescence.

Western blot - Anti-VASP antibody (AB89829)
  • WB

Unknown

Western blot - Anti-VASP antibody (AB89829)

All lanes:

Western blot - Anti-VASP antibody (ab89829) at 1 µg/mL

All lanes:

human spleen tissue lysate at 50 µg

Predicted band size: 39 kDa

Observed band size: 42 kDa

true

주요 정보

Host species

Mouse

Clonality

Polyclonal

Isotype

IgG

Carrier free

Yes

Reacts with

Human

Applications

WB, ICC/IF

applications

Immunogen

Recombinant Full Length Protein corresponding to Human VASP.

P50552

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대체품

Primary Antibodies

AB109541

Anti-VASP (phospho S156) antibody [EPR1065(2)]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-VASP (phospho S156) antibody [EPR1065(2)] (AB109541)

  • 0
  • 0
Primary Antibodies

AB242021

Anti-VASP (phospho S239) antibody [EPR21734] - BSA and Azide free

RabMAb|Recombinant

Immunoprecipitation - Anti-VASP (phospho S239) antibody [EPR21734] - BSA and Azide free (AB242021)

  • 0
  • 0
Primary Antibodies

AB47268

Anti-VASP (phospho S157) antibody

Western blot - Anti-VASP (phospho S157) antibody (AB47268)

  • 4
  • 2
Primary Antibodies

AB194747

Anti-VASP (phospho S239) antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-VASP (phospho S239) antibody (AB194747)

  • 5
  • 1
Primary Antibodies

AB218619

Anti-VASP (phospho S239) antibody [EPR21734]

RabMAb|Recombinant|Trial Size

Immunoprecipitation - Anti-VASP (phospho S239) antibody [EPR21734] (AB218619)

  • 0
  • 0
Primary Antibodies

AB109321

Anti-VASP antibody [EPR1337(2)]

20ul selling size|RabMAb|Recombinant|Trial Size

Immunoprecipitation - Anti-VASP antibody [EPR1337(2)] (AB109321)

  • 0
  • 0
Primary Antibodies

AB231823

Anti-VASP antibody [EPR1337(2)] - BSA and Azide free

RabMAb|Recombinant|KO Validated

Immunoprecipitation - Anti-VASP antibody [EPR1337(2)] - BSA and Azide free (AB231823)

  • 0
  • 0

보완 제품

Primary Antibodies

AB194747

Anti-VASP (phospho S239) antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-VASP (phospho S239) antibody (AB194747)

  • 5
  • 1
Primary Antibodies

AB47268

Anti-VASP (phospho S157) antibody

Western blot - Anti-VASP (phospho S157) antibody (AB47268)

  • 4
  • 2
Primary Antibodies

AB8227

Anti-beta Actin antibody - Loading Control

BOND RX™ Validated|Lab Essentials

Western blot - Anti-beta Actin antibody - Loading Control (AB8227)

  • 5
  • 104
Primary Antibodies

AB109316

Anti-Zyxin antibody [EPR4302]

20ul selling size|BOND RX™ Validated|RabMAb|Recombinant

Flow Cytometry (Intracellular) - Anti-Zyxin antibody [EPR4302] (AB109316)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "10 µg/mL", "ICCIF-species-notes": "<p></p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein A
보관 버퍼
pH: 7.4 Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

VASP also known as Vasodilator-Stimulated Phosphoprotein is a 46-50 kDa protein involved in actin filament assembly and elongation. It plays an important role in cellular motility and the maintenance of cell shape. VASP is expressed in many cell types but is notably present in platelets and endothelial cells. It is an important player in signal transduction pathways that lead to cytoskeletal reorganization influencing cell movement and adhesion dynamics.
Biological function summary

VASP is an important component in cell movement regulation. It acts within a larger complex of actin-binding proteins that control the assembly of actin filaments. This protein influences cell adhesion migration and signal transduction processes. Through these actions VASP influences cellular responses to environmental cues making it essential for cellular dynamics and integrity during development and wound healing.

Pathways

VASP connects to significant signaling pathways such as the PI3K/Akt pathway and the cAMP pathway. It often interacts with proteins like c-Abl tyrosine kinase and Mena contributing to actin dynamics regulation. These pathways are critical for transducing signals from extracellular environments to intracellular responses allowing for coordinated cellular functions in processes such as cell migration and growth.

VASP plays a role in cardiovascular disease and cancer-related metastasis due to its function in cell motility and adhesion. Abnormal VASP activity is associated with impaired endothelial cell function and contributes to atherosclerosis development. Additionally it interacts with proteins like Mena and fascin in cancer cells aiding in metastatic progression by enhancing motility and invasive capabilities.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation.
See full target information VASP

대체 명칭 보기

Vasodilator-stimulated phosphoprotein, VASP
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Life (Basel, Switzerland) 14: PubMed38672781

2024

Approaches to Characterize and Quantify Extracellular Vesicle Surface Conjugation Efficiency.

Applications

Unspecified application

Species

Unspecified reactive species

Leora Goldbloom-Helzner,Harjn Bains,Aijun Wang
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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