JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB242270

violetFluor™ 450 Anti-Thy1.2 antibody [30-H12]

Be the first to review this product! 리뷰 제출

|

(0 출판물)

Anti-Thy1.2 antibody [30-H12] conjugated to violetFluor™ 450 - suitable for flow cytometry, and reacts with mouse samples. Clone [30-H12] is a rat monoclonal antibody and one of the most commonly used clones for flow cytometry.

Design your panel with our interactive flow cytometry panel builder. Click here.
1 이미지
Flow Cytometry - violetFluor™ 450 Anti-Thy1.2 antibody [30-H12] (AB242270)
  • Flow Cyt

Supplier Data

Flow Cytometry - violetFluor™ 450 Anti-Thy1.2 antibody [30-H12] (AB242270)

Flow cytometric analysis of C57Bl/6 splenocytes staining CD90 / Thy1 using FITC Anti-Mouse CD3e and 0.25 μg ab242270 (right panel) or 0.25 μg violet- Fluor™ 450 Rat IgG2b isotype control (left panel).

관련 conjugated 항체와 다양한 조성의 항체 (2)

  • 778 PE/Cy7®

    PE/Cy7® Anti-Thy1.2 antibody [30-H12]

  • 695 PerCP/Cy5.5®

    PerCP/Cy5.5® Anti-Thy1.2 antibody [30-H12]

주요 정보

Host species

Rat

Clonality

Monoclonal

Clone number

30-H12

Isotype

IgG2b

Conjugation

violetFluor™ 450

Excitation/Emission

Ex: 405nm, Em: 450nm

Carrier free

No

Reacts with

Mouse

Applications

Flow Cyt

applications

Specificity

The 30-H12 antibody reacts with mouse CD90.2 (Thy1.2). 30-H12 does not react with the CD90.1 allele expressed in mouse strains such as PL and AKR.

style
left-column

대체품

Primary Antibodies

AB269343

PE Anti-Thy1.2 antibody [1aG4/C5]

Flow Cytometry - PE Anti-Thy1.2 antibody [1aG4/C5] (AB269343)

  • 0
  • 0

보완 제품

Primary Antibodies

AB24982

Cy5 ® Anti-CD45.1 antibody [A20]

  • 0
  • 0
Primary Antibodies

AB252149

Alexa Fluor® 488 Anti-CD4 antibody [EPR20122]

RabMAb|Recombinant

Flow Cytometry - Alexa Fluor® 488 Anti-CD4 antibody [EPR20122] (AB252149)

  • 0
  • 0
Primary Antibodies

AB237365

Alexa Fluor® 647 Anti-CD8 alpha antibody [EPR21769]

BOND RX™ Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Alexa Fluor® 647 Anti-CD8 alpha antibody [EPR21769] (AB237365)

  • 0
  • 0
Primary Antibodies

AB303467

Alexa Fluor® 647 Anti-Ly6g antibody [EPR22909-135]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Alexa Fluor® 647 Anti-Ly6g antibody [EPR22909-135] (AB303467)

  • 0
  • 0
style
left-column

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p>Use 0.25 μg.</p>" } } }
style
left-column
style
left-column

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification
Purification 관련 사항
Purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.
보관 버퍼
pH: 7.2 Preservative: 0.09% Sodium azide Constituents: 0.87% Sodium chloride, 0.12% Sodium dihydrogen phosphate, 0.1% Gelatin
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
보관 정보
Store in the dark
style
left-column

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Thy1.2 also known as Thy-1 antigen or CD90 is a glycoprotein with a mass of approximately 25-35 kDa. It is expressed on the surface of many cell types including neurons thymocytes and fibroblasts. Thy1.2 is part of the immunoglobulin superfamily and plays a role in cell-cell interactions adhesion and signal transduction. Researchers often study Thy1.2 in the context of the mouse model as it is a well-defined target in murine immunology and neurobiology.
Biological function summary

The Thy1.2 protein influences cellular adhesion and migration processes. It does not form part of a known complex but regulates multiple interactions at the cellular membrane. In the nervous system Thy1.2 impacts neurite outgrowth and synapse formation. In the immune system it modulates T-cell activation and cytokine production. These actions make Thy1.2 integral to cellular communication and response mechanisms.

Pathways

Thy1.2 plays significant roles in signal transduction and cell adhesion pathways. It participates in the MAPK/ERK pathway which is important for cell growth and survival. Thy1.2 interacts closely with integrin proteins facilitating cell-matrix adhesion and signaling. This connection supports cellular processes that depend on environmental cues impacting both development and immune responses.

Thy1.2 shows significant associations with cancer and fibrosis. In cancer abnormal Thy1.2 expression or function can influence tumor growth and metastasis often in conjunction with other proteins such as integrins and CD44. In fibrosis Thy1.2 impacts fibroblast activity and extracellular matrix regulation leading to tissue remodeling. Studies explore how modulating Thy1.2 levels or function might offer therapeutic potential in these conditions.
style
left-column
style
left-column

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

타겟 정보

May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
See full target information Thy1

대체 명칭 보기

CD90, Thy-1, Thy1, Thy-1 membrane glycoprotein, Thy-1 antigen
style
left-column
style
left-column
style
right-column

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com