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AB63572

Anti-Vitamin D Receptor (phospho S208) antibody

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Rabbit Polyclonal Vitamin D Receptor phospho S208 antibody. Suitable for ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human VDR pS208.
1 이미지
Immunocytochemistry/ Immunofluorescence - Anti-Vitamin D Receptor (phospho S208) antibody (AB63572)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-Vitamin D Receptor (phospho S208) antibody (AB63572)

Immunofluorescent staining of A549 cells, using ab63572 at a 1/500 dilution, minus immunising peptide (left image) and plus immunising peptide (right image).

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF

applications

Immunogen

Synthetic Peptide within Human VDR pS208. The exact immunogen used to generate this antibody is proprietary information.

P11473

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/500 - 1/1000", "ICCIF-species-notes": "<p></p>" } } }

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
Purification 관련 사항
Purified from rabbit antiserum by affinity chromatography using epitope specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
보관 버퍼
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
보관 정보
Stable for 12 months at -20°C

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

타겟 정보

Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells (PubMed : 10678179, PubMed : 15728261, PubMed : 16913708, PubMed : 28698609, PubMed : 37478846). Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR (PubMed : 28698609). The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes (PubMed : 28698609). Plays a central role in calcium homeostasis (By similarity). Also functions as a receptor for the secondary bile acid lithocholic acid (LCA) and its metabolites (PubMed : 12016314, PubMed : 32354638).
See full target information VDR pS208

대체 명칭 보기

NR1I1, VDR, Vitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1

제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

The Journal of experimental medicine 207:731-50 PubMed20368581

2010

Targeting iron homeostasis induces cellular differentiation and synergizes with differentiating agents in acute myeloid leukemia.

Applications

WB

Species

Human

Celine Callens,Séverine Coulon,Jerome Naudin,Isabelle Radford-Weiss,Nicolas Boissel,Emmanuel Raffoux,Pamella Huey Mei Wang,Saurabh Agarwal,Houda Tamouza,Etienne Paubelle,Vahid Asnafi,Jean-Antoine Ribeil,Philippe Dessen,Danielle Canioni,Olivia Chandesris,Marie Therese Rubio,Carole Beaumont,Marc Benhamou,Hervé Dombret,Elizabeth Macintyre,Renato C Monteiro,Ivan C Moura,Olivier Hermine
제품이 사용된 논문 모두 보기

Product promise

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