AB93871

Anti-WDR11 antibody

Name: Anti-WDR11 antibody
Brand: Abcam Limited
SKU: AB93871
Rating: 4 (4 reviews)

(4 리뷰들)

(6 제품이 사용된 논문 )

Rabbit Polyclonal WDR11 antibody. Suitable for IP, WB and reacts with Human samples. Cited in 6 publications. Immunogen corresponding to Synthetic Peptide within Human WDR11 aa 1150 to C-terminus.

2 이미지

Unknown

Immunoprecipitation - Anti-WDR11 antibody (AB93871)

ab93871 at 1 µg/ml detecting WDR11 in HeLa whole cell lysate by WB following IP.
Lane 1 : IP with an antibody which recognizes an upstream epitope of WDR11
Lane 2 : ab93871 at 3µg/mg of lysate
Lane 3 : control IgG.
In each case, 1 mg of lysate was used for IP and 20% of the IP was loaded.
Detection : Chemiluminescence an with exposure time of 10 seconds

All lanes:

Immunoprecipitation - Anti-WDR11 antibody (ab93871)

Predicted band size: 137 kDa

false

Unknown

Western blot - Anti-WDR11 antibody (AB93871)

All lanes:

Western blot - Anti-WDR11 antibody (ab93871) at 0.04 µg/mL

Lane 1:

Hela whole cell lysate at 50 µg

Lane 2:

Hela whole cell lysate at 15 µg

Lane 3:

Hela whole cell lysate at 5 µg

Lane 4:

293T cell lysate at 50 µg

Predicted band size: 137 kDa

true

Exposure time: 3min

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

WB, IP

applications

Immunogen

Synthetic Peptide within Human WDR11 aa 1150 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q9BZH6

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "2-5 µg/mg of lysate", "IP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000 - 1/10000", "WB-species-notes": "<p></p>" }, "Chimpanzee": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Gorilla": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Immunogen

보관 버퍼

pH: 6.8 - 7.4 Preservative: 0.09% Sodium azide Constituents: Tris buffered saline, 0.1% BSA

배송 시 보관 조건

Blue Ice

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

+4°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

Involved in the Hedgehog (Hh) signaling pathway, is essential for normal ciliogenesis (PubMed : 29263200). Regulates the proteolytic processing of GLI3 and cooperates with the transcription factor EMX1 in the induction of downstream Hh pathway gene expression and gonadotropin-releasing hormone production (PubMed : 29263200). WDR11 complex facilitates the tethering of Adaptor protein-1 complex (AP-1)-derived vesicles. WDR11 complex acts together with TBC1D23 to facilitate the golgin-mediated capture of vesicles generated using AP-1 (PubMed : 29426865).

See full target information WDR11

대체 명칭 보기

BRWD2, KIAA1351, WDR15, WDR11, WD repeat-containing protein 11, Bromodomain and WD repeat-containing protein 2, WD repeat-containing protein 15

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제품이 사용된 논문 (6)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Cell discovery 11:23 PubMed40097395

2025

Trans-Golgi network tethering factors regulate TBK1 trafficking and promote the STING-IFN-I pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Jinrui Wang,Shenghui Niu,Xiao Hu,Tianxing Li,Shengduo Liu,Yingfeng Tu,Zehua Shang,Lin Zhao,Pinglong Xu,Jingwen Lin,Lu Chen,Daniel D Billadeau,Da Jia

Cell 187:4272-4288.e20 PubMed39013469

2024

The WDR11 complex is a receptor for acidic-cluster-containing cargo proteins.

Applications

Unspecified application

Species

Unspecified reactive species

Huaqing Deng,Guowen Jia,Ping Li,Yingying Tang,Lin Zhao,Qin Yang,Jia Zhao,Jinrui Wang,Yingfeng Tu,Xin Yong,Sitao Zhang,Xianming Mo,Daniel D Billadeau,Zhaoming Su,Da Jia

Journal of virology 96:e0182721 PubMed35020472

2022

Human Cytomegalovirus Hijacks WD Repeat Domain 11 for Virion Assembly Compartment Formation and Virion Morphogenesis.

Applications

Unspecified application

Species

Unspecified reactive species

Bo Yang,YongXuan Yao,Han Cheng,Xian-Zhang Wang,Yue-Peng Zhou,Sheng-Nan Huang,Xuehui Ma,Hong Yang,Jinpeng Wu,Xuan Jiang,Shuang Cheng,Jin-Yan Sun,Wen-Bo Zeng,Jason Chen,Fu-Kun Zhang,Hong-Jie Shen,Jian-Yang Gu,Michael A McVoy,William J Britt,Sitang Gong,Min-Hua Luo

European journal of human genetics : EJHG 29:1663-1668 PubMed34413497

2021

Biallelic loss-of-function variants in WDR11 are associated with microcephaly and intellectual disability.

Applications

Unspecified application

Species

Unspecified reactive species

Natja Haag,Ene-Choo Tan,Matthias Begemann,Lars Buschmann,Florian Kraft,Petra Holschbach,Angeline H M Lai,Maggie Brett,Ganeshwaran H Mochida,Stephanie DiTroia,Lynn Pais,Jennifer E Neil,Muna Al-Saffar,Laila Bastaki,Christopher A Walsh,Ingo Kurth,Cordula Knopp

Nature communications 9:596 PubMed29426865

2018

The WDR11 complex facilitates the tethering of AP-1-derived vesicles.

Applications

WB, ICC/IF

Species

Unspecified reactive species, Unspecified reactive species

Paloma Navarro Negredo,James R Edgar,Paul T Manna,Robin Antrobus,Margaret S Robinson

Journal of virology 89:9841-52 PubMed26178983

2015

Cellular Protein WDR11 Interacts with Specific Herpes Simplex Virus Proteins at the trans-Golgi Network To Promote Virus Replication.

Applications

Unspecified application

Species

Unspecified reactive species

Kathryne E Taylor,Karen L Mossman

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-WDR11 antibody

Immunoprecipitation - Anti-WDR11 antibody (AB93871)

Western blot - Anti-WDR11 antibody (AB93871)

주요 정보

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

보완 제품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

특성 및 보관 정보

제형

Purification 테크닉

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

제품 프로토콜

타겟 정보

대체 명칭 보기

제품이 사용된 논문 (6)

Product promise