JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB235355

Anti-ZMAT5 antibody

Be the first to review this product! 리뷰 제출

|

(1 출판물)

Rabbit Polyclonal ZMAT5 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human ZMAT5.

대체 명칭 보기

Zinc finger matrin-type protein 5, U11/U12 small nuclear ribonucleoprotein 20 kDa protein, U11/U12 snRNP 20 kDa protein, U11/U12-20K, ZMAT5

2 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZMAT5 antibody (AB235355)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZMAT5 antibody (AB235355)

Paraffin-embedded human endometrial cancer tissue stained for ZMAT5 using ab235355 at 1/100 dilution in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZMAT5 antibody (AB235355)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZMAT5 antibody (AB235355)

Paraffin-embedded human tonsil tissue stained for ZMAT5 using ab235355 at 1/100 dilution in immunohistochemical analysis.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human ZMAT5.

Q9UDW3

style
left-column

보완 제품

Primary Antibodies

AB237811

Anti-ZNF695 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZNF695 antibody (AB237811)

  • 0
  • 0
Primary Antibodies

AB235784

Anti-XRRA1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-XRRA1 antibody (AB235784)

  • 0
  • 0
Primary Antibodies

AB176689

Anti-ZNF384 antibody

Immunoprecipitation - Anti-ZNF384 antibody (AB176689)

  • 5
  • 1
Primary Antibodies

AB237623

Anti-WDFY2 antibody

Immunocytochemistry/ Immunofluorescence - Anti-WDFY2 antibody (AB237623)

  • 0
  • 0
style
left-column

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>" } } }
style
left-column
style
left-column

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein G
Purification 관련 사항
Purity >95%
보관 버퍼
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
style
left-column

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

ZMAT5 also known as zinc finger matrin-type 5 is a protein that functions primarily by binding nucleic acids. It has a molecular mass of approximately 57 kDa. ZMAT5 contains zinc finger motifs which enable it to interact with RNA and possibly DNA suggesting a role in post-transcriptional regulation. It is mainly expressed in the nucleus of cells with significant expression reported in various tissues including the brain heart and liver.
Biological function summary

ZMAT5 plays a role in regulating mRNA stability and splicing. It may form part of a larger ribonucleoprotein complex interacting with other proteins and RNA to influence gene expression at a post-transcriptional level. The binding of ZMAT5 to specific RNA sequences indicates specialized functions which can affect how cells respond to different conditions by altering how genes are expressed.

Pathways

The presence of ZMAT5 is significant in RNA-related pathways including the regulation of mRNA splicing. Within these pathways it interacts with spliceosome components which are important for the precise removal of introns from pre-mRNA. ZMAT5 may influence the activity of related proteins like SRSF1 and hnRNPA1 which are key players in the splicing mechanism and control diverse cellular processes.

Research links ZMAT5 with neurodegenerative disorders and certain cancers. Abnormalities in its splicing functions can relate to diseases like amyotrophic lateral sclerosis (ALS) where disrupted RNA processing is a common hallmark. Furthermore dysregulation of ZMAT5 expression or function could connect with cancer progression involving proteins like SRSF6 which modulate similar pathways and are often deregulated in tumors.
style
left-column
style
left-column

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

타겟 정보

See full target information ZMAT5
style
left-column

제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

The Journal of clinical endocrinology and metabolism 107:3328-3340 PubMed36074910

2022

Premature Ovarian Insufficiency in CLPB Deficiency: Transcriptomic, Proteomic and Phenotypic Insights.

Applications

Unspecified application

Species

Unspecified reactive species

Elena J Tucker,Megan J Baker,Daniella H Hock,Julia T Warren,Sylvie Jaillard,Katrina M Bell,Rajini Sreenivasan,Shabnam Bakhshalizadeh,Chloe A Hanna,Nikeisha J Caruana,Saskia B Wortmann,Shamima Rahman,Robert D S Pitceathly,Jean Donadieu,Aurelia Alimi,Vincent Launay,Paul Coppo,Sophie Christin-Maitre,Gorjana Robevska,Jocelyn van den Bergen,Brianna L Kline,Katie L Ayers,Phoebe N Stewart,David A Stroud,Diana Stojanovski,Andrew H Sinclair
제품이 사용된 논문 모두 보기
style
left-column
style
left-column
style
right-column

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com