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AB225924

Anti-ZNF169 antibody

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(2 제품이 사용된 논문 )

Rabbit Polyclonal ZNF169 antibody. Suitable for WB, IHC-P and reacts with Human, Mouse samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human ZNF169 aa 1-100.

대체 명칭 보기

Zinc finger protein 169, ZNF169

2 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZNF169 antibody (AB225924)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZNF169 antibody (AB225924)

Paraffin embedded human colon cancer tissue stained for ZNF169 with ab225924 (1/100 dilution) in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZNF169 antibody (AB225924)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZNF169 antibody (AB225924)

Paraffin embedded human small intestine tissue stained for ZNF169 with ab225924 (1/100 dilution) in immunohistochemical analysis.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Human ZNF169 aa 1-100. The exact immunogen used to generate this antibody is proprietary information.

Q14929

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
보관 버퍼
pH: 7.3 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

ZNF169 also known as Zinc Finger Protein 169 is a transcription factor that belongs to the zinc finger family. This protein weighs about 84 kDa. It functions by binding to specific DNA sequences regulating gene expression. Expression of ZNF169 is found in various tissues including the brain and testes. It plays a role in numerous cellular processes due to its ability to modulate transcription.
Biological function summary

This protein acts as a regulatory element in cellular differentiation and proliferation. It does not form part of a larger protein complex but influences the expression of genes involved in these processes. ZNF169 impacts cellular responses to environmental changes by regulating genes necessary for cell cycle progression and differentiation.

Pathways

Several pathways involve ZNF169 in cell signaling and gene regulation. One important pathway is the DNA damage response pathway where it interacts with proteins like p53 which mediates cell cycle arrest or apoptosis. Another is the WNT signaling pathway related to its role in cellular proliferation and differentiation. ZNF169's influence on these pathways highlights its involvement in maintaining cellular dynamics and stability.

Scientists have associated ZNF169 with cancer and intellectual disability conditions. Overexpression or dysregulation of ZNF169 has been linked to tumorigenesis often interacting with proteins like p53 that importantly determine cell fate after DNA damage. In intellectual disabilities abnormal expression of ZNF169 affects genes essential for proper neurological function implicating its role in cognitive development.

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

타겟 정보

May be involved in transcriptional regulation.
See full target information ZNF169

제품이 사용된 논문 (2)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Cell division 20:3 PubMed39875985

2025

ZNF169 promotes thyroid cancer progression via upregulating FBXW10.

Applications

Unspecified application

Species

Unspecified reactive species

Wen Luo,Qiyu Xiao,Ying Fu

Oncology reports 51: PubMed38666541

2024

Overexpression of ZNF169 promotes the growth and proliferation of colorectal cancer cells via the upregulation of ANKZF1.

Applications

Unspecified application

Species

Unspecified reactive species

Jie Zhang,Ye Wang,Shiyang Hou,Xiaoqian Chi,Danyang Ding,Mei Xue,Mengqiao Zhang,Jing Wang,Junfang Shuai,Haiying Sun,Qiang Gao,Chunbo Kang
제품이 사용된 논문 모두 보기

Product promise

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