AB117803

Anti-ZNF687 antibody

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Rabbit Polyclonal ZNF687 antibody. Suitable for IP and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human ZNF687 aa 100-150.

대체 명칭 보기

KIAA1441, ZNF687, Zinc finger protein 687

1 이미지

Unknown

Immunoprecipitation - Anti-ZNF687 antibody (AB117803)

Lane 1 : Staining of ZNF687 in HeLa whole cell lysate immunoprecipitated using ab117803 at 6 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Lane 2 : control IgG. Predicted band size : 130 kDa. Exposure time : 3 minutes

All lanes:

Immunoprecipitation - Anti-ZNF687 antibody (ab117803)

Predicted band size: 129 kDa

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주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

applications

Immunogen

Synthetic Peptide within Human ZNF687 aa 100-150. The exact immunogen used to generate this antibody is proprietary information.

Q8N1G0

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "2-10 µg/mg of lysate", "IP-species-notes": "<p></p>" }, "Baboon": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "" }, "Chimpanzee": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "" }, "Gorilla": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "" }, "Rhesus monkey": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "" } } }

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Immunogen

Purification 관련 사항

ab117803 was affinity purified using an epitope specific to ZNF687 immobilized on solid support.

보관 버퍼

pH: 7 - 8 Preservative: 0.09% Sodium azide Constituents: 99% Tris citrate/phosphate

배송 시 보관 조건

Blue Ice

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

+4°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

ZNF687 also known as zinc finger protein 687 is a transcription factor with a known molecular mass of approximately 137 kDa. This protein contains multiple zinc finger motifs that enable its binding to specific DNA sequences regulating the transcription of certain genes. ZNF687 is expressed in various tissues including the brain liver and bone marrow. Its ability to bind DNA is critical for controlling gene expression related to cell proliferation and differentiation.

Biological function summary

ZNF687 functions as a regulatory protein involved in gene expression playing an important role in cellular growth and differentiation. It does not appear to be part of a larger protein complex but acts through binding to specific DNA sequences. The protein helps regulate genes involved in hematopoiesis and neural development suggesting a role in the development and maintenance of these tissues.

Pathways

ZNF687 contributes to gene transcription pathways important for cellular growth and development. It interfaces with signaling pathways such as the MAPK/ERK pathway which is significant for cell proliferation and survival. ZNF687 associates with other transcription factors and its function affects proteins like MYC and FOS which are central to these pathways. By regulating these pathways ZNF687 impacts cellular responses to internal and external stimuli.

ZNF687 is connected to several conditions including osteosarcoma and Paget's disease of bone. Mutations or dysregulation of ZNF687 have been implicated in these diseases potentially through interactions with proteins like SQSTM1 which plays a role in bone remodeling. Research continues to explore ZNF687's contributions to these conditions indicating its relevance in understanding and possibly targeting these diseases.

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

May be involved in transcriptional regulation.

See full target information ZNF687

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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Journal of translational medicine 23:220 PubMed39985078

2025

SPICE1 promotes osteosarcoma growth by enhancing the deubiquitination of FASN mediated by USP10.

Applications

Unspecified application

Species

Unspecified reactive species

Weilai Tong,Xinsheng Xie,Zhiguo Shu,Jiangbo Nie,Xianhe Yang,Feng Yang,Zhili Liu,Jiaming Liu

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-ZNF687 antibody

Immunoprecipitation - Anti-ZNF687 antibody (AB117803)

주요 정보

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

보완 제품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

특성 및 보관 정보

제형

Purification 테크닉

Purification 관련 사항

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

추가 정보

Biological function summary

Pathways

제품 프로토콜

타겟 정보

제품이 사용된 논문 (1)

Product promise