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AB41752

Human EAAT2 peptide

4

(1 리뷰)

|

(1 출판물)

Human EAAT2 peptide is a Synthetic blocking peptide. >90% and suitable for BL.

주요 정보

Purity

>90%

Tags

Tag free

Applications

BL

applications

Biologically active

No

Accession

P43004-1

Animal free

No

Carrier free

No

Species

Human

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보완 제품

Proteins & Peptides

AB105573

Recombinant Human S100 Calcium Binding Protein A13/S100A13 (His tag N-Terminus)

SDS-PAGE - Recombinant Human S100 Calcium Binding Protein A13/S100A13 (His tag N-Terminus) (AB105573)

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Primary Antibodies

AB205248

Anti-EAAT2 antibody [EPR19798]

20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Frozen sections) - Anti-EAAT2 antibody [EPR19798] (AB205248)

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  • 0
Primary Antibodies

AB303530

Anti-MiTF antibody [EPR26363-10]

BOND RX™ Validated|20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MiTF antibody [EPR26363-10] (AB303530)

  • 4
  • 1
Primary Antibodies

AB172730

Rabbit IgG, monoclonal [EPR25A] - Isotype Control

RabMAb|Advanced Validation|Recombinant

Flow Cytometry - Rabbit IgG, monoclonal [EPR25A] - Isotype Control (AB172730)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "BL": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"1 µg/mL", "notes":"<p></p>" } } }
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제품 세부 정보

Reconstitution instructions:

- First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.

- If the peptide doesn't dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.

- Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.

- Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.

- Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

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서열 정보

[{"linker":null,"sequence":null,"proteinLength":null,"predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":0,"aminoAcidStart":0,"nature":"Synthetic","expressionSystem":null,"accessionNumber":"P43004","tags":[]}]
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특성 및 보관 정보

제형
Lyophilized
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
Ambient
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False
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일반 정보

기능

Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed : 14506254, PubMed : 15265858, PubMed : 26690923, PubMed : 7521911). Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion (PubMed : 14506254). Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport (PubMed : 14506254). Essential for the rapid removal of released glutamate from the synaptic cleft, and for terminating the postsynaptic action of glutamate (By similarity).

서열 유사성

Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. SLC1A2 subfamily.

Post-translational modifications

Glycosylated.. Palmitoylation at Cys-38 is not required for correct subcellular localization, but is important for glutamate uptake activity.

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제품 프로토콜

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타겟 정보

Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed : 14506254, PubMed : 15265858, PubMed : 26690923, PubMed : 7521911). Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion (PubMed : 14506254). Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport (PubMed : 14506254). Essential for the rapid removal of released glutamate from the synaptic cleft, and for terminating the postsynaptic action of glutamate (By similarity).
See full target information SLC1A2

대체 명칭 보기

EAAT2, GLT1, SLC1A2, Excitatory amino acid transporter 2, Glutamate/aspartate transporter II, Sodium-dependent glutamate/aspartate transporter 2, Solute carrier family 1 member 2
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

American journal of physiology. Regulatory, integr 303:R291-300 PubMed22696576

2012

Altered astrocyte glutamate transporter regulation of hypothalamic neurosecretory neurons in heart failure rats.

Applications

Unspecified application

Species

Unspecified reactive species

Evgeniy S Potapenko,Vinicia C Biancardi,Yiqiang Zhou,Javier E Stern
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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