AB18661
Mouse PSD95 peptide is a Synthetic blocking peptide. >90% and suitable for BL.
보완 제품
Reagents, Controls & Accessories
AB325994
Prestained Protein Ladder - Mid-range molecular weight (11-180 kDa, 4-color)
- 0
- 0
Primary Antibodies
AB238135
Anti-PSD95 antibody [EPR23124-118] - Synaptic Marker
BOND RX™ Validated|KO Validated|RabMAb|Recombinant|Lab Essentials|20ul selling size
![Western blot - Anti-PSD95 antibody [EPR23124-118] - Synaptic Marker (AB238135)](https://content.abcam.com/products/images/psd95-antibody-epr23124-118-synaptic-marker-ab238135--western-blot-img164430.jpg)
- 5
- 5
Reactivity 정보
{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "BL": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
제품 세부 정보
- First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
- If the peptide doesn't dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
- Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
- Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
- Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.
- If the peptide doesn't dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
- Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
- Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
- Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.
서열 정보
[{"linker":null,"sequence":null,"proteinLength":null,"predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":0,"aminoAcidStart":0,"nature":"Synthetic","expressionSystem":null,"accessionNumber":"P78352","tags":[]}]
특성 및 보관 정보
제형
Liquid
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False
타겟 정보
Postsynaptic scaffolding protein that plays a critical role in synaptogenesis and synaptic plasticity by providing a platform for the postsynaptic clustering of crucial synaptic proteins. Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. Also regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression (By similarity). Under basal conditions, cooperates with FYN to stabilize palmitoyltransferase ZDHHC5 at the synaptic membrane through FYN-mediated phosphorylation of ZDHHC5 and its subsequent inhibition of association with endocytic proteins (PubMed : 26334723).
대체 명칭 보기
PSD95, DLG4, Disks large homolog 4, Postsynaptic density protein 95, Synapse-associated protein 90, PSD-95, SAP-90, SAP90
제품이 사용된 논문 (2)
Recent publications for all applications. Explore the 전체 목록and refine your search
Neuroscience 208:27-40 PubMed22342969
2012
Ovarian steroids increase spinogenetic proteins in the macaque dorsal raphe.
Applications
BL
Species
Unspecified reactive species
H M Rivera,C L Bethea
Journal of neuroendocrinology 23:65-73 PubMed20874778
2010
Synaptic reorganisation of the medial amygdala during puberty.
Applications
BL
Species
Unspecified reactive species
B M Cooke
Product promise
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