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AB240866

Recombinant 46 kDa surface antigen protein (His tag)

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Recombinant 46 kDa surface antigen protein (His tag) is a Mycoplasma hyopneumoniae 232 Full Length protein, in the 28 to 416 aa range, expressed in Yeast, with >90%, suitable for SDS-PAGE.

대체 명칭 보기

mhp511, p46, 46 kDa surface antigen

1 이미지
SDS-PAGE - Recombinant 46 kDa surface antigen protein (His tag) (AB240866)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant 46 kDa surface antigen protein (His tag) (AB240866)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel analysis of ab240866.

주요 정보

Purity

>90% SDS-PAGE

발현 시스템

Yeast

Tags

His tag N-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Mycoplasma hyopneumoniae 232

보관 버퍼

pH: 7.2 - 7.4 Constituents: Tris buffer, 50% Glycerol (glycerin, glycerine)

storage-buffer

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보완 제품

Proteins & Peptides

AB276642

Recombinant Human HNT protein (His tag)

SDS-PAGE - Recombinant Human HNT protein (His tag) (AB276642)

  • 0
  • 0
Proteins & Peptides

AB224847

Recombinant Invasin protein (His tag)

SDS-PAGE - Recombinant Invasin protein (His tag) (AB224847)

  • 0
  • 0
Proteins & Peptides

AB225663

Recombinant Rabies Virus Glycoprotein (His tag)

SDS-PAGE - Recombinant Rabies Virus Glycoprotein (His tag) (AB225663)

  • 0
  • 0
Primary Antibodies

AB1187

HRP Anti-6X His tag® antibody

Western blot - HRP Anti-6X His tag® antibody (AB1187)

  • 4
  • 12
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"linker":null,"sequence":"CGQTESGSTSDSKPQAETLKHKVSNDSIRIALTDPDNPRWISAQKDIISYVDETEAATSTITKNQDAQNNWLTQQANLSPAPKGFIIAPENGSGVGTAVNTIADKGIPIVAYDRLITGSDKYDWYVSFDNEKVGELQGLSLAAGLLGKEDGAFDSIDQMNEYLKSHMPQETISFYTIAGSQDDNNSQYFYNGAMKVLKELMKNSQNKIIDLSPEGENAVYVPGWNYGTAGQRIQSFLTINKDPAGGNKIKAVGSKPASIFKGFLAPNDGMAEQAITKLKLEGFDTQKIFVTGQDYNDKAKTFIKDGDQNMTIYKPDKVLGKVAVEVLRVLIAKKNKASRSEVENELKAKLPNISFKYDNQTYKVQGKNINTILVSPVIVTKANVDNPDA","proteinLength":"Full Length","predictedMolecularWeight":"44.5 kDa","actualMolecularWeight":null,"aminoAcidEnd":416,"aminoAcidStart":28,"nature":"Recombinant","expressionSystem":"Yeast","accessionNumber":"P0C0J7","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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특성 및 보관 정보

제형
Liquid
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
보관 정보
Avoid freeze / thaw cycle
False
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

The 46 kDa surface antigen also known as 46 kDa protein plays an important role mechanically in the function of various parasitic organisms. This protein is expressed on the surface of cells where it interacts with the host immune system. The protein's molecular mass is approximately 46 kilodaltons which relates to its alternate name and facilitates its identification in laboratory settings. Researchers often study this protein due to its involvement in the initial stages of infection where it aids in evading the host's immune response.
Biological function summary

The 46 kDa surface antigen participates in immune evasion by forming part of a complex that interferes with host-pathogen recognition. This complex helps the organism adapt to the host immune environment. Researchers have identified its expression in different stages of the life cycle of the parasite indicating its adaptive role. The protein aids in the ability of the parasite to establish infection successfully which makes it an attractive target for therapeutic interventions.

Pathways

The 46 kDa surface antigen is involved in pathways related to immune modulation and pathogenicity. It plays a role in the host-pathogen interaction pathway contributing to the mechanism by which the pathogen escapes immune detection. During this process it interacts with other surface proteins such as variant surface glycoproteins to help the parasite elude immune responses. The protein's activity within these pathways is essential for the survival and propagation of the parasite within the host organism.

The 46 kDa surface antigen is implicated in infections caused by protozoan parasites including diseases such as African sleeping sickness. Its presence on the parasite surface allows it to avoid detection by the human immune system prolonging infection and contributing to disease pathology. The antigen can also influence the actions of other surface proteins such as the 65 kDa protein which are critical to the parasite's ability to persist within the host. Identifying and targeting this protein can be important to developing effective treatment strategies against these infections.
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일반 정보

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제품 프로토콜

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타겟 정보

See full target information p46
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Product promise

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