AB43041

Recombinant Cytomegalovirus pp65 protein

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(6 제품이 사용된 논문 )

Recombinant Cytomegalovirus pp65 protein is a Human herpesvirus 5 strain AD169 Full Length protein, expressed in Escherichia coli, with >95%, suitable for ELISA, WB.

주요 정보

Purity

>95% SDS-PAGE

Sepharose derived purification.

발현 시스템

Escherichia coli

Applications

WB, ELISA

applications

Biologically active

Accession

P06725-1

Animal free

Carrier free

Species

Human herpesvirus 5 strain AD169

보관 버퍼

pH: 8 Constituents: 48.048% Urea, 0.394% Tris HCl, 0.039% 2-Mercaptoethanol

storage-buffer

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

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제품 세부 정보

Specificity: Immunoreactive with sera of CMV-infected individuals.

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서열 정보

[{"linker":null,"sequence":"","proteinLength":"Full Length","predictedMolecularWeight":"62.9 kDa","actualMolecularWeight":null,"aminoAcidEnd":0,"aminoAcidStart":0,"nature":"Recombinant","expressionSystem":null,"accessionNumber":null,"tags":[{"tag":"6x His","terminus":"N-Terminus"}]}]

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특성 및 보관 정보

제형

Liquid

배송 시 보관 조건

Blue Ice

적절한 단기 보관 조건

-20°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

False

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일반 정보

기능

Counteracts the host antiviral immune response when activated and phosphorylated, by preventing host IRF3 from entering the nucleus (PubMed : 15452220). Also inhibits the type I interferon production by inactivating the enzymatic activity of DNA sensor CGAS without affecting STING1 (PubMed : 29263269, PubMed : 40243337). Participates in the transactivation of viral major immediate-early genes by the recruitment of host IFI16 to the promoters pf these genes (PubMed : 20504932).

서열 유사성

Belongs to the herpesviridae pp65 family.

Post-translational modifications

Phosphorylation may play a role in the localization of the protein.. S-nitrosylated. Nitrosylation decreases the inhibition of host CGAS.

Subcellular localisation

Host nucleus

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제품 프로토콜

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

See full target information UL83

대체 명칭 보기

65 kDa phosphoprotein, pp65, 65 kDa matrix phosphoprotein, Phosphoprotein UL83, Tegument protein UL83, UL83

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제품이 사용된 논문 (6)

Recent publications for all applications. Explore the 전체 목록 and refine your search

PloS one 20:e0321392 PubMed40193826

2025

Assessment of antigen immunogenicity formulated in minigenes transfected into antigen-presenting cells.

Applications

Unspecified application

Species

Unspecified reactive species

María A Villota-Alava,María A Alfaro-Marenco,Carlos A Clavijo-Ramírez,Manuel A Patarroyo,Carlos A Parra-López

BMC gastroenterology 23:333 PubMed37759163

2023

Zerumbone ameliorates the inflammatory response and organ damage in severe acute pancreatitis via the ROS/NF-κB pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Fengmei Zhang,Dongjia Xu

iScience 26:105928 PubMed36619367

2023

Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region.

Applications

Unspecified application

Species

Unspecified reactive species

Marc Emmenegger,Elena De Cecco,David Lamparter,Raphaël P B Jacquat,Julien Riou,Dominik Menges,Tala Ballouz,Daniel Ebner,Matthias M Schneider,Itzel Condado Morales,Berre Doğançay,Jingjing Guo,Anne Wiedmer,Julie Domange,Marigona Imeri,Rita Moos,Chryssa Zografou,Leyla Batkitar,Lidia Madrigal,Dezirae Schneider,Chiara Trevisan,Andres Gonzalez-Guerra,Alessandra Carrella,Irina L Dubach,Catherine K Xu,Georg Meisl,Vasilis Kosmoliaptsis,Tomas Malinauskas,Nicola Burgess-Brown,Ray Owens,Stephanie Hatch,Juthathip Mongkolsapaya,Gavin R Screaton,Katharina Schubert,John D Huck,Feimei Liu,Florence Pojer,Kelvin Lau,David Hacker,Elsbeth Probst-Müller,Carlo Cervia,Jakob Nilsson,Onur Boyman,Lanja Saleh,Katharina Spanaus,Arnold von Eckardstein,Dominik J Schaer,Nenad Ban,Ching-Ju Tsai,Jacopo Marino,Gebhard F X Schertler,Nadine Ebert,Volker Thiel,Jochen Gottschalk,Beat M Frey,Regina R Reimann,Simone Hornemann,Aaron M Ring,Tuomas P J Knowles,Milo A Puhan,Christian L Althaus,Ioannis Xenarios,David I Stuart,Adriano Aguzzi

PLoS pathogens 15:e1007914 PubMed31356650

2019

Identification of adipocyte plasma membrane-associated protein as a novel modulator of human cytomegalovirus infection.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaohua Ye,Xun Gui,Daniel C Freed,Zhiqiang Ku,Leike Li,Yuanzhi Chen,Wei Xiong,Xuejun Fan,Hang Su,Xi He,Richard R Rustandi,John W Loughney,Ningning Ma,Amy S Espeseth,Jian Liu,Hua Zhu,Dai Wang,Ningyan Zhang,Tong-Ming Fu,Zhiqiang An

Scientific reports 9:9998 PubMed31292492

2019

Characterisation of a human antibody that potentially links cytomegalovirus infection with systemic lupus erythematosus.

Applications

Unspecified application

Species

Unspecified reactive species

Jie Ying Jacklyn Neo,Seng Yin Kelly Wee,Isabelle Bonne,Sen Hee Tay,Manfred Raida,Vojislav Jovanovic,Anna-Marie Fairhurst,Jinhua Lu,Brendon J Hanson,Paul A MacAry

Nature medicine 25:977-987 PubMed31110348

2019

IFN-γ-independent immune markers of Mycobacterium tuberculosis exposure.

Applications

Unspecified application

Species

Unspecified reactive species

Lenette L Lu,Malisa T Smith,Krystle K Q Yu,Corinne Luedemann,Todd J Suscovich,Patricia S Grace,Adam Cain,Wen Han Yu,Tanya R McKitrick,Douglas Lauffenburger,Richard D Cummings,Harriet Mayanja-Kizza,Thomas R Hawn,W Henry Boom,Catherine M Stein,Sarah M Fortune,Chetan Seshadri,Galit Alter

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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Recombinant Cytomegalovirus pp65 protein

주요 정보

Purity

발현 시스템

Tags

Applications

Biologically active

Accession

Animal free

Carrier free

Species

보관 버퍼

보완 제품

Reagents, Controls & Accessories

Proteins & Peptides

Proteins & Peptides

Primary Antibodies

Proteins & Peptides

Reactivity 정보

제품 세부 정보

서열 정보

특성 및 보관 정보

제형

배송 시 보관 조건

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

일반 정보

기능

서열 유사성

Post-translational modifications

Subcellular localisation

제품 프로토콜

타겟 정보

대체 명칭 보기

제품이 사용된 논문 (6)

Product promise