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AB106864

Recombinant E. coli deoC protein (His tag N-Terminus)

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Recombinant E. coli deoC protein (His tag N-Terminus) is a Escherichia coli K-12 Full Length protein, in the 1 to 259 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE, Mass Spec.

대체 명칭 보기

dra, thyR, b4381, JW4344, deoC, Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase

2 이미지
SDS-PAGE - Recombinant E. coli deoC protein (His tag N-Terminus) (AB106864)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant E. coli deoC protein (His tag N-Terminus) (AB106864)

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

SDS-PAGE - Recombinant E. coli deoC protein (His tag N-Terminus) (AB106864)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant E. coli deoC protein (His tag N-Terminus) (AB106864)

15% SDS-PAGE analysis of 3μg ab106864.

주요 정보

Purity

>95% SDS-PAGE

ab106864 is purified using conventional chromatography techniques.

발현 시스템

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE, Mass Spec

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Escherichia coli K-12

보관 버퍼

pH: 8 Constituents: 10% Glycerol (glycerin, glycerine), 0.316% Tris HCl, 0.0308% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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보완 제품

Proteins & Peptides

AB104677

Recombinant E. coli fimC protein (His tag N-Terminus)

SDS-PAGE - Recombinant E. coli fimC protein (His tag N-Terminus) (AB104677)

  • 0
  • 0
Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Proteins & Peptides

AB107143

Recombinant E. coli glsA1 protein (His tag N-Terminus)

SDS-PAGE - Recombinant E. coli glsA1 protein (His tag N-Terminus) (AB107143)

  • 0
  • 0
Secondary Antibodies

AB41500

Rabbit Anti-Chicken IgY H&L (15nm Gold)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"linker":null,"sequence":"MGSSHHHHHHSSGLVPRGSHMTDLKASSLRALKLMDLTTLNDDDTDEKVIALCHQAKTPVGNTAAICIYPRFIPIARKTLKEQGTPEIRIATVTNFPHGNDDIDIALAETRAAIAYGADEVDVVFPYRALMAGNEQVGFDLVKACKEACAAANVLLKVIIETGELKDEALIRKASEISIKAGADFIKTSTGKVAVNATPESARIMMEVIRDMGVEKTVGFKPAGGVRTAEDAQKYLAIADELFGADWADARHYRFGASSLLASLLKALGHGDGKSASSY","proteinLength":"Full Length","predictedMolecularWeight":"29.9 kDa","actualMolecularWeight":null,"aminoAcidEnd":259,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P0A6L0","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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특성 및 보관 정보

제형
Liquid
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

DeoC also known as deoxyribose-phosphate aldolase is an enzyme that plays a mechanical role in catalyzing the cleavage of deoxyribose-5-phosphate into glyceraldehyde-3-phosphate and acetaldehyde. This enzyme weighs approximately 23 kDa. deoC is typically expressed in bacterial cells especially within Escherichia coli where it is involved in DNA metabolism by-products breakdown.
Biological function summary

The enzyme deoC functions as part of the pentose phosphate pathway critical for cellular functions by contributing to nucleotide synthesis and energy generation. In its role deoC doesn't form part of a larger complex but functions independently. It acts on intermediates in nucleotide salvage pathways therefore playing a role in optimizing cellular resources.

Pathways

DeoC integrates into the non-oxidative branch of the pentose phosphate pathway facilitating the conversion of sugar phosphates. It interacts with other enzymes like ribose-5-phosphate isomerase and transketolase which are pivotal in these metabolic pathways. These interactions highlight its essential role in connecting nucleotide metabolism and glycolysis.

Researchers have explored deoC's implications in bacterial infections. Its activity significantly impacts the pathogen's survival and virulence influencing disorders related to bacterial persistence. While deoC itself is not directly linked to human diseases it plays an important role in bacterial life cycle and disrupts the metabolic processes that can reduce the bacterial load. This makes it an indirect target for antibiotic strategies.
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일반 정보

기능

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate (PubMed : 11598300, PubMed : 17905878, PubMed : 6749498). Can also catalyze the double aldol condensation of three acetaldehyde molecules, leading to the formation of 2,4,6-trideoxyhexose (Ref.5).

서열 유사성

Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.

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제품 프로토콜

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타겟 정보

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate (PubMed : 11598300, PubMed : 17905878, PubMed : 6749498). Can also catalyze the double aldol condensation of three acetaldehyde molecules, leading to the formation of 2,4,6-trideoxyhexose (Ref.5).
See full target information deoC
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Product promise

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