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AB171507

Recombinant Human ACBD6 protein (His tag N-Terminus)

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Recombinant Human ACBD6 protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 282 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.

대체 명칭 보기

Acyl-CoA-binding domain-containing protein 6, ACBD6

1 이미지
SDS-PAGE - Recombinant Human ACBD6 protein (His tag N-Terminus) (AB171507)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human ACBD6 protein (His tag N-Terminus) (AB171507)

15% SDS-PAGE analysis of ab171507 (3μg).

주요 정보

Purity

>90% SDS-PAGE

ab171507 is purified using conventional chromatography techniques.

발현 시스템

Escherichia coli

Tags

His tag N-Terminus

Applications

Mass Spec, SDS-PAGE

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 8 Constituents: 20% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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보완 제품

Primary Antibodies

AB234788

Anti-PLAC8 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PLAC8 antibody (AB234788)

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Proteins & Peptides

AB171501

Recombinant Human PLAC8 protein (denatured) (His tag N-Terminus)

SDS-PAGE - Recombinant Human PLAC8 protein (denatured) (His tag N-Terminus) (AB171501)

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Primary Antibodies

AB171978

Anti-TIMMDC1/C3orf1 antibody [EPR11807]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-TIMMDC1/C3orf1 antibody [EPR11807] (AB171978)

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  • 0
Primary Antibodies

AB251916

Anti-FLVCR1 antibody

Immunocytochemistry/ Immunofluorescence - Anti-FLVCR1 antibody (AB251916)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"linker":null,"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMASSFLPAGAITGDSGGELSSGDDSGEVEFPHSPEIEETSCLAELFEKAAAHLQGLIQVASREQLLYLYARYKQVKVGNCNTPKPSFFDFEGKQKWEAWKALGDSSPSQAMQEYIAVVKKLDPGWNPQIPEKKGKEANTGFGGPVISSLYHEETIREEDKNIFDYCRENNIDHITKAIKSKNVDVNVKDEEGRALLHWACDRGHKELVTVLLQHRADINCQDNEGQTALHYASACEFLDIVELLLQSGADPTLRDQDGCLPEEVTGCKTVSLVLQRHTTGKA","proteinLength":"Full Length","predictedMolecularWeight":"33.5 kDa","actualMolecularWeight":null,"aminoAcidEnd":282,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q9BR61","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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특성 및 보관 정보

제형
Liquid
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

ACBD6 also known as Acyl-CoA binding domain-containing protein 6 is a protein with a molecular weight of approximately 32 kDa. It acts by binding to acyl-CoA molecules and impacting cellular lipid metabolism. Widely expressed in human tissues ACBD6 shows notably higher expression in the heart and testis. This protein plays an important role in maintaining lipid homeostasis within cells.
Biological function summary

ACBD6 modulates lipid signalling processes and participates in cellular lipid droplet formation. It is part of the larger acyl-CoA binding protein family which is known for regulating lipid metabolism. By interacting with these lipid molecules ACBD6 influences cellular energy dynamics and storage capacity. In some contexts it forms complexes with other proteins to modulate lipid processing and serve metabolic functions.

Pathways

ACBD6 integrates into lipid metabolism pathways where it affects fatty acid binding and transport. The protein interacts with components of the triacylglycerol biosynthesis pathway making connections with members like the lipase family. ACBD6’s relationships with these pathways highlight its role in the cellular process of storing and utilizing lipids for energy and structural purposes.

ACBD6 has been linked to diseases related to dysregulated lipid metabolism such as obesity and type 2 diabetes. Dysfunctions in ACBD6 activity can contribute to abnormal lipid accumulation and impaired energy balance. It connects to metabolic syndrome through pathways shared with proteins like LPL known for their roles in lipid metabolism disorders. Understanding the impact of ACBD6 in these conditions can help in developing targeted therapeutic strategies.
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일반 정보

기능

Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18 : 1-CoA, lower affinity for unsaturated C20 : 4-CoA, and very weak affinity for saturated C16 : 0-CoA. Does not bind fatty acids. Plays a role in protein N-myristoylation (PubMed : 37951597).

Subcellular localisation

Nucleus

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제품 프로토콜

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타겟 정보

Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18 : 1-CoA, lower affinity for unsaturated C20 : 4-CoA, and very weak affinity for saturated C16 : 0-CoA. Does not bind fatty acids. Plays a role in protein N-myristoylation (PubMed : 37951597).
See full target information ACBD6
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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