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AB101943

Recombinant Human ARL5A protein (His tag N-Terminus)

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Recombinant Human ARL5A protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 179 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.

대체 명칭 보기

ARFLP5, ARL5, ARL5A, ADP-ribosylation factor-like protein 5A

1 이미지
SDS-PAGE - Recombinant Human ARL5A protein (His tag N-Terminus) (AB101943)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human ARL5A protein (His tag N-Terminus) (AB101943)

15% SDS-PAGE analysis of 3µg ab101943.

주요 정보

Purity

>90% SDS-PAGE

ab101943 is purified using conventional chromatography techniques.

발현 시스템

Escherichia coli

Tags

His tag N-Terminus

Applications

Mass Spec, SDS-PAGE

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 8 Constituents: 20% Glycerol (glycerin, glycerine), 0.316% Tris HCl, 0.0308% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.00348% PMSF

storage-buffer

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보완 제품

Primary Antibodies

AB218531

Anti-SEH1L antibody [EPR20851]

RabMAb|Recombinant|Trial Size

Immunoprecipitation - Anti-SEH1L antibody [EPR20851] (AB218531)

  • 0
  • 0
Proteins & Peptides

AB256229

Recombinant human Follistatin protein (Active)

Bioactive

Functional Studies - Recombinant human Follistatin protein (Active) (AB256229)

  • 0
  • 0
Primary Antibodies

AB20670

Anti-Islet 1 antibody - Neural Stem Cell Marker

BOND RX™ Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Islet 1 antibody - Neural Stem Cell Marker (AB20670)

  • 4
  • 17
Primary Antibodies

AB221884

Anti-HB9/HLXB9/MNX1 antibody

Immunocytochemistry/ Immunofluorescence - Anti-HB9/HLXB9/MNX1 antibody (AB221884)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"linker":null,"sequence":"MGSSHHHHHHSSGLVPRGSHMGSHMGILFTRIWRLFNHQEHKVIIVGLDNAGKTTILYQFSMNEVVHTSPTIGSNVEEIVINNTRFLMWDIGGQESLRSSWNTYYTNTEFVIVVVDSTDRERISVTREELYKMLAHEDLRKAGLLIFANKQDVKECMTVAEISQFLKLTSIKDHQWHIQACCALTGEGLCQGLEWMMSRLKIR","proteinLength":"Full Length","predictedMolecularWeight":"23.3 kDa","actualMolecularWeight":null,"aminoAcidEnd":179,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q9Y689","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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특성 및 보관 정보

제형
Liquid
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

ARL5A also known as ADP-ribosylation factor-like protein 5A is a membrane-associated small GTPase with a molecular mass of approximately 21 kDa. It belongs to the ARF family involved in vesicular trafficking and signaling processes. ARL5A is expressed in various tissues with higher expression in brain and testis. The protein exhibits a GTP-binding with intrinsic GTPase activity playing an important role in the regulation of intracellular vesicle transport.
Biological function summary

ARL5A functions as part of a larger molecular complex. The protein participates in endosomal trafficking processes and is associated with the Golgi apparatus. By modulating the dynamics of the Golgi-endosome transport system ARL5A influences vesicle budding and cargo sorting. It interacts with other proteins such as ARL5B to facilitate the formation and movement of vesicles in the cell.

Pathways

This protein participates in the intracellular trafficking-related signaling pathways. It plays a part in the Wnt signaling pathway influencing vesicular movement between organelles. ARL5A interacts with proteins like GGA proteins which are adaptors that mediate cargo sorting and potentially links it with other important regulators in these pathways. This interaction allows cells to maintain homeostasis and properly respond to signaling events.

Mutant ARL5A has associations with neurodevelopmental disorders pointing to its significance in neural development. The protein's aberrant functions can disrupt normal cellular mechanisms contributing to disease states. It connects with proteins like ARF6 also a member of the ARF family which are implicated in the same regulatory networks. Understanding ARL5A's roles in these conditions could provide insights into potential therapeutic targets.
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일반 정보

기능

Lacks ADP-ribosylation enhancing activity.

서열 유사성

Belongs to the small GTPase superfamily. Arf family.

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제품 프로토콜

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타겟 정보

Lacks ADP-ribosylation enhancing activity.
See full target information ARL5A
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Product promise

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