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AB276317

Recombinant Human ASAM protein (His tag)

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Recombinant Human ASAM protein (His tag) is a Human Fragment protein, in the 1 to 233 aa range, expressed in HEK 293 cells, with >97%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.

대체 명칭 보기

ACAM, ASAM, UNQ318/PRO363, CLMP, CXADR-like membrane protein, Adipocyte adhesion molecule, Coxsackie- and adenovirus receptor-like membrane protein, CAR-like membrane protein

1 이미지
SDS-PAGE - Recombinant Human ASAM protein (His tag) (AB276317)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human ASAM protein (His tag) (AB276317)

SDS-PAGE analysis of ab276317

주요 정보

Purity

>97% SDS-PAGE

Endotoxin 레벨

< 1 EU/µg

발현 시스템

HEK 293 cells

Tags

His tag C-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 7.4 Constituents: PBS

storage-buffer

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보완 제품

Reagents, Controls & Accessories

AB325997

Prestained Protein Ladder - Extra broad molecular weight (3-250 kDa, 5-color)

SDS-PAGE - Prestained Protein Ladder - Extra broad molecular weight (3-250 kDa, 5-color) (AB325997)

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  • 0
Proteins & Peptides

AB174398

Recombinant Human FAM84B protein (His tag N-Terminus)

SDS-PAGE - Recombinant Human FAM84B protein (His tag N-Terminus) (AB174398)

  • 0
  • 0
Primary Antibodies

AB108930

Anti-Tenascin C antibody [EPR4219]

RabMAb|Recombinant|KO Validated|20ul selling size

Immunohistochemistry (Frozen sections) - Anti-Tenascin C antibody [EPR4219] (AB108930)

  • 4
  • 17
Primary Antibodies

AB254556

Anti-Galanin antibody [EPR22496-308]

BOND RX™ Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Galanin antibody [EPR22496-308] (AB254556)

  • 4
  • 1
Primary Antibodies

AB302769

Anti-SPON2 antibody [EPR25828-46] - BSA and Azide free (Detector)

RabMAb|Recombinant

Sandwich ELISA - Anti-SPON2 antibody [EPR25828-46] - BSA and Azide free (Detector) (AB302769)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"linker":null,"sequence":"MSLLLLLLLVSYYVGTLGTHTEIKRVAEEKVTLPCHHQLGLPEKDTLDIEWLLTDNEGNQKVVITYSSRHVYNNLTEEQKGRVAFASNFLAGDASLQIEPLKPSDEGRYTCKVKNSGRYVWSHVILKVLVRPSKPKCELEGELTEGSDLTLQCESSSGTEPIVYYWQRIREKEGEDERLPPKSRIDYNHPGRVLLQNLTMSYSGLYQCTAGNEAGKESCVVRVTVQYVQSIGM","proteinLength":"Fragment","predictedMolecularWeight":"25.8 kDa","actualMolecularWeight":null,"aminoAcidEnd":233,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"Q9H6B4","tags":[{"tag":"His","terminus":"C-Terminus"}]}]
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특성 및 보관 정보

제형
Lyophilized
배송 시 보관 조건
Ambient - Can Ship with Ice
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

The ASAM protein also known as the Adipocyte plasma Membrane Associated Protein (APPL1) is a transmembrane protein with a mass around 34 kDa. It is highly expressed in adipose tissue and endothelial cells but appears across a range of tissues. The ASAM protein plays a role in adhesion processes by facilitating cell-cell interactions and is important in maintaining cellular architecture. It interacts with multiple binding partners suggesting diverse functionality and involvement in cellular signaling pathways.
Biological function summary

The ASAM protein has significant roles in cellular adhesion and signaling. As part of the plasma membrane it modulates interactions between cells and their environment contributing to tissue development and repair. It is not typically known to be part of a larger complex but its ability to bind with other proteins highlights its versatility in cellular regulation. Researchers understand it better in the context of cell structural dynamics and communication processes.

Pathways

Research identifies the ASAM protein as a player in the insulin signaling pathway and the cellular adhesion pathway. In insulin signaling it interacts with proteins such as IGF1R and PI3K connecting it to metabolic regulation and homeostasis. The cellular adhesion pathway finds ASAM working with cadherins and integrins which emphasizes its function in cell communication and structural integrity. Its engagement in these pathways indicates its influence on metabolic processes and cellular response mechanisms.

The ASAM protein shows relevance in conditions like diabetes and obesity. Its involvement in insulin signaling aligns it with metabolic disorders where dysregulation affects glucose uptake and lipid metabolism. Histological studies indicate ASAM interactions with other proteins like FAK and AMPK in the context of these diseases. This connection suggests its potential as a biomarker for metabolic syndromes providing insight into disease development and therapeutic target exploration.
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일반 정보

기능

May be involved in the cell-cell adhesion. May play a role in adipocyte differentiation and development of obesity. Is required for normal small intestine development.

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제품 프로토콜

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타겟 정보

May be involved in the cell-cell adhesion. May play a role in adipocyte differentiation and development of obesity. Is required for normal small intestine development.
See full target information CLMP
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Product promise

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