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AB219461

Recombinant Human B3GNT1 protein (His tag C-Terminus)

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Recombinant Human B3GNT1 protein (His tag C-Terminus) is a Human Fragment protein, in the 29 to 397 aa range, expressed in Baculovirus infected insect cells, with >90%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.

대체 명칭 보기

B3GALT7, B3GNT1, B3GNT2, Beta-3-Gx-T7, BGnT-1, Beta3Gn-T1, Beta3Gal-T7, Beta3GalT7, b3Gal-T7, BGnT-2, Beta3Gn-T2

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SDS-PAGE - Recombinant Human B3GNT1 protein (His tag C-Terminus) (AB219461)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human B3GNT1 protein (His tag C-Terminus) (AB219461)

15% SDS-PAGE - Recombinant Human B3GNT1 protein (His tag) (ab219461) at 3 μg.

주요 정보

Purity

>90% SDS-PAGE

Affinity purified

Endotoxin 레벨

< 1 EU/µg

발현 시스템

Baculovirus infected insect cells

Tags

His tag C-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 7.4 Constituents: PBS, 10% Glycerol (glycerin, glycerine)

storage-buffer

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보완 제품

Primary Antibodies

AB236291

Anti-B3GNT1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-B3GNT1 antibody (AB236291)

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Primary Antibodies

AB133534

Anti-Rad51 antibody [EPR4030(3)]

20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Rad51 antibody [EPR4030(3)] (AB133534)

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Proteins & Peptides

AB163575

Recombinant Human SERINC1 protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human SERINC1 protein (GST tag N-Terminus) (AB163575)

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  • 0
Proteins & Peptides

AB276879

Recombinant Mouse CHST3 protein (His tag)

SDS-PAGE - Recombinant Mouse CHST3 protein (His tag) (AB276879)

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  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p>40-57 kDa SDS-PAGE under reducing conditions.</p>" } } }
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서열 정보

[{"linker":null,"sequence":"ADPKSSSQEKNGKGEVIIPKEKFWKISTPPEAYWNREQEKLNRQYNPILSMLTNQTGEAGRLSNISHLNYCEPDLRVTSVVTGFNNLPDRFKDFLLYLRCRNYSLLIDQPDKCAKKPFLLLAIKSLTPHFARRQAIRESWGQESNAGNQTVVRVFLLGQTPPEDNHPDLSDMLKFESEKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSCPDTEFVFKGDDDVFVNTHHILNYLNSLSKTKAKDLFIGDVIHNAGPHRDKKLKYYIPEVVYSGLYPPYAGGGGFLYSGHLALRLYHITDQVHLYPIDDVYTGMCLQKLGLVPEKHKGFRTFDIEEKNKNNICSYVDLMLVHSRKPQEMIDIWSQLQSAHLKCHHHHHH","proteinLength":"Fragment","predictedMolecularWeight":"43.5 kDa","actualMolecularWeight":null,"aminoAcidEnd":397,"aminoAcidStart":29,"nature":"Recombinant","expressionSystem":"Baculovirus infected insect cells","accessionNumber":"Q9NY97","tags":[{"tag":"His","terminus":"C-Terminus"}]}]
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

B3GNT1 also known as UDP-GlcNAc:betaGal beta-13-N-acetylglucosaminyltransferase 1 is an enzyme that participates in glycosylation processes by transferring N-acetylglucosamine from UDP-GlcNAc to polylactosamine chains playing an important role in the synthesis of poly-N-acetyllactosamine. This protein has a mass of approximately 43 kDa and predominantly expresses in tissues that produce substantial amounts of glycosylated molecules such as the brain and the gastrointestinal tract.
Biological function summary

B3GNT1 contributes to the synthesis of glycan structures that are important for cell-cell interactions. It functions as an independent enzyme rather than as part of a larger enzymatic complex. The activity of B3GNT1 impacts the production of complex-type N- and O-glycans which support cellular adhesion signaling and immune recognition. Such functions make B3GNT1 significant in various physiological processes particularly in the development and maintenance of tissues.

Pathways

B3GNT1 is integral to the glycosaminoglycan biosynthesis and glycoprotein metabolic pathways. It interacts with other enzymes involved in these pathways such as beta-14-galactosyltransferase to construct poly-N-acetyllactosamine structures. The connectivity between B3GNT1 and other glycosyltransferases ensures proper assembly and function of glycan-containing molecules necessary for diverse biological activities.

Aberrant expression or malfunction of B3GNT1 links to conditions like congenital disorders of glycosylation and certain cancers. Abnormal glycosylation patterns sometimes involving related proteins such as FUT8 which is another glycosyltransferase can lead to defective cellular signaling and contribute to these pathologies. Understanding these connections helps in exploring therapeutic targets and diagnostic markers for glycosylation-related diseases.
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일반 정보

기능

Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains. Shows a marked preference for Gal(beta1-4)Glc(NAc)-based acceptors (PubMed : 9892646). Probably constitutes the main polylactosamine synthase.

서열 유사성

Belongs to the glycosyltransferase 31 family.

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제품 프로토콜

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타겟 정보

Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains. Shows a marked preference for Gal(beta1-4)Glc(NAc)-based acceptors (PubMed : 9892646). Probably constitutes the main polylactosamine synthase.
See full target information B3GNT2
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Product promise

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