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AB160437

Recombinant Human B4GALT5 protein (GST tag N-Terminus)

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(1 출판물)

Recombinant Human B4GALT5 protein (GST tag N-Terminus) is a Human Fragment protein, in the 48 to 151 aa range, expressed in Wheat germ, suitable for ELISA, WB.
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SDS-PAGE - Recombinant Human B4GALT5 protein (GST tag N-Terminus) (AB160437)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human B4GALT5 protein (GST tag N-Terminus) (AB160437)

ab160437 on a 12.5% SDS-PAGE stained with Coomassie Blue.

주요 정보

발현 시스템

Wheat germ

Tags

GST tag N-Terminus

Applications

ELISA, WB

applications

Biologically active

No

Accession

O43286-1

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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보완 제품

Proteins & Peptides

AB164250

Recombinant Human CPEB4 protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human CPEB4 protein (GST tag N-Terminus) (AB164250)

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Primary Antibodies

AB110398

Anti-B4GALT5 antibody

Western blot - Anti-B4GALT5 antibody (AB110398)

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  • 0
Proteins & Peptides

AB276342

Recombinant Human Neuropeptide Y protein (Fc Chimera)

SDS-PAGE - Recombinant Human Neuropeptide Y protein (Fc Chimera) (AB276342)

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Primary Antibodies

AB281152

Anti-Neuropeptide Y antibody [EPR23483-18] - BSA and Azide free (Capture)

BOND RX™ Validated|RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-Neuropeptide Y antibody [EPR23483-18] - BSA and Azide free (Capture) (AB281152)

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  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"linker":null,"sequence":"AQGILIRDNVRTIGAQVYEQVLRSAYAKRNSSVNDSDYPLDLNHSETFLQTTTFLPEDFTYFANHTCPERLPSMKGPIDINMSEIGMDYIHELFSKDPTIKLGG","proteinLength":"Fragment","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":151,"aminoAcidStart":48,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"O43286","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Proprietary technique
배송 시 보관 조건
Dry Ice
적절한 단기 보관 조건
-80°C
적절한 장기 보관 조건
-80°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

B4GALT5 also known as beta-14-galactosyltransferase 5 is an enzyme critical for glycosylation processes. This enzyme has a molecular weight of approximately 43 kDa. It adds galactose to specific carbohydrate structures and plays a role in forming lactose and other glycan structures. This enzyme is part of the larger beta-14-galactosyltransferase family and is found in the Golgi apparatus. It is expressed in various tissues with significant activity in the liver and kidney and to a certain extent in the brain.
Biological function summary

B4GALT5 is involved in the synthesis of complex glycoconjugates and lactose. It contributes to the N-linked and O-linked glycosylation of proteins which are essential for protein folding stability and cell signaling. B4GALT5 forms part of the enzyme complex responsible for elongating glycan chains cooperating with other glycosyltransferases. Through its enzymatic activity it affects cell-cell interactions host-pathogen recognition and immune responses.

Pathways

B4GALT5 is an important component of the glycan biosynthesis and metabolism pathways. Its action affects the glycoprotein quality control and folding pathways. In these processes it works alongside other glycosyltransferases such as B4GALT1 ensuring proper glycoconjugate formation and modification. These pathways influence developmental processes immune system functions and normal cellular operations.

B4GALT5 has links to congenital disorders of glycosylation and cancer. Abnormal glycosylation can alter cell adhesion and migration contributing to tumorigenesis and metastasis. The enzyme shows altered expression levels in certain cancers suggesting its role as a potential biomarker. B4GALT5 has associations with other proteins like E-cadherin where changes in glycosylation patterns can influence cancer progression and immune evasion.
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제품 프로토콜

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타겟 정보

Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer) (PubMed : 24498430). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation (By similarity). Plays a role in the glycosylation of BMPR1A and regulation of its protein stability (By similarity). Essential for extraembryonic development during early embryogenesis (By similarity).
See full target information B4GALT5

대체 명칭 보기

Beta4Gal-T5, b4Gal-T5, Lactosylceramide synthase, LacCer synthase, B4GALT5
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록and refine your search

Analytica chimica acta 1205:339739 PubMed35414399

2022

Peptide-based simple detection of SARS-CoV-2 with electrochemical readout.

Applications

Unspecified application

Species

Unspecified reactive species

Dayana Soto,Jahir Orozco
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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