Recombinant Human BRPF3 protein (GST tag N-Terminus)
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Recombinant Human BRPF3 protein (GST tag N-Terminus) is a Human Fragment protein, in the 576 to 701 aa range, expressed in Escherichia coli, with >80%, suitable for SDS-PAGE.
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KIAA1286, BRPF3, Bromodomain and PHD finger-containing protein 3
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human BRPF3 protein (GST tag N-Terminus) (AB198073)
4-20% SDS-PAGE analysis of ab198073 (2 μg) with Coomassie staining.
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기능
Scaffold subunit of various histone acetyltransferase (HAT) complexes, such as the MOZ/MORF and HBO1 complexes, which have a histone H3 acetyltransferase activity (PubMed : 16387653, PubMed : 26620551, PubMed : 26677226). Plays a role in DNA replication initiation by directing KAT7/HBO1 specificity towards histone H3 'Lys-14' acetylation (H3K14ac), thereby facilitating the activation of replication origins (PubMed : 26620551). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity (PubMed : 16387653).
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