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AB276550

Recombinant Human BTN3A2 protein (His tag)

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Recombinant Human BTN3A2 protein (His tag) is a Human Fragment protein, in the 1 to 248 aa range, expressed in HEK 293 cells, with >95%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.

대체 명칭 보기

BT3.2, BTF3, BTF4, BTN3A2, Butyrophilin subfamily 3 member A2

1 이미지
SDS-PAGE - Recombinant Human BTN3A2 protein (His tag) (AB276550)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human BTN3A2 protein (His tag) (AB276550)

SDS-PAGE analysis of ab276550

주요 정보

Purity

>95% SDS-PAGE

Endotoxin 레벨

< 1 EU/µg

발현 시스템

HEK 293 cells

Tags

His tag C-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 7.4 Constituents: PBS

storage-buffer

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

서열 정보

[{"linker":null,"sequence":"MKMASSLAFLLLNFHVSLLLVQLLTPCSAQFSVLGPSGPILAMVGEDADLPCHLFPTMSAETMELKWVSSSLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQDGDFYEKALVELKVAALGSNLHVEVKGYEDGGIHLECRSTGWYPQPQIQWSNAKGENIPAVEAPVVADGVGLYEVAASVIMRGGSGEGVSCIIRNSLLGLEKTASISIADPFFRSAQPW","proteinLength":"Fragment","predictedMolecularWeight":"25.1 kDa","actualMolecularWeight":null,"aminoAcidEnd":248,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"P78410","tags":[{"tag":"His","terminus":"C-Terminus"}]}]

특성 및 보관 정보

제형
Lyophilized
배송 시 보관 조건
Ambient - Can Ship with Ice
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

BTN3A2 also known as Butyrophilin Subfamily 3 Member A2 is a protein involved in the immune response. It has a molecular weight of approximately 35 kDa. BTN3A2 expresses in a variety of tissues especially in immune-related cells like T-cells. It forms part of the butyrophilin family known for modulating immune cell functions. The protein is anchored in the cell membrane indicating its role in cell signaling.
Biological function summary

BTN3A2 participates in immune regulation and modulation of T-cell activity. It functions as part of the BTN3A family complex working alongside BTN3A1 and BTN3A3. This protein family influences T-cell receptor signaling and activation contributing to the immune system's ability to respond to pathogens and infections. BTN3A2 plays a role in linking extracellular and intracellular signals that affect immune cell behavior.

Pathways

BTN3A2 integrates within the adaptive immune signaling pathways. One key pathway is the T-cell receptor signaling pathway where BTN3A2 collaborates with BTN3A1 to modulate immune responses. Another significant involvement is in the gamma delta T-cell activation pathway. BTN3A2 partners with proteins like phosphoantigens and other butyrophilins emphasizing its role in controlling T-cell mediated immune functions.

BTN3A2 relates to certain autoimmune conditions and cancers. Altered expression of BTN3A2 connects to disorders like psoriasis where dysregulated immune activity plays a part. The protein also connects to chronic lymphocytic leukemia as abnormal BTN3A2 signaling could drive leukemic T-cell behavior. Through these diseases BTN3A2 associates with related proteins such as BTN3A1 and histone deacetylases interacting in pathways disrupted in these conditions.

일반 정보

기능

Plays a role in T-cell responses in the adaptive immune response. Inhibits the release of IFNG from activated T-cells.

서열 유사성

Belongs to the immunoglobulin superfamily. BTN/MOG family.

Post-translational modifications

N-glycosylated.

제품 프로토콜

타겟 정보

Plays a role in T-cell responses in the adaptive immune response. Inhibits the release of IFNG from activated T-cells.
See full target information BTN3A2

Product promise

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