Recombinant Human CD300a protein (His tag) is a Human Fragment protein, in the 1 to 178 aa range, expressed in HEK 293 cells, with >90%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.
대체 명칭 보기
CD300a, CMRF35H, IGSF12, HSPC083, CD300A, CMRF35-like molecule 8, CLM-8, CD300 antigen-like family member A, CMRF-35-H9, CMRF35-H, IRC1/IRC2, Immunoglobulin superfamily member 12, Inhibitory receptor protein 60, NK inhibitory receptor, CMRF35-H9, IgSF12, IRp60
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human CD300a protein (His tag) (AB276481)
SDS-PAGE analysis of ab276481
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서열 정보
특성 및 보관 정보
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일반 정보
기능
Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation (PubMed : 10746781, PubMed : 16339535, PubMed : 9701027). Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6 (PubMed : 22043923).
서열 유사성
Belongs to the CD300 family.
Post-translational modifications
Phosphorylated on tyrosine.. N-glycosylated.
타겟 정보
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