Recombinant Human CIKS/ACT1 protein (GST tag N-Terminus)
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Recombinant Human CIKS/ACT1 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 565 aa range, expressed in Wheat germ, suitable for ELISA, WB.
대체 명칭 보기
C6orf2, C6orf4, C6orf5, C6orf6, TRAF3IP2, E3 ubiquitin ligase TRAF3IP2, Adapter protein CIKS, Connection to IKK and SAPK/JNK, E3 ubiquitin-protein ligase CIKS, Nuclear factor NF-kappa-B activator 1, TRAF3-interacting protein 2, ACT1
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human CIKS/ACT1 protein (GST tag N-Terminus) (AB161141)
ab161141 on a 12.5% SDS-PAGE stained with Coomassie Blue.
Reactivity 정보
제품 세부 정보
서열 정보
특성 및 보관 정보
제형
Purification 테크닉
배송 시 보관 조건
적절한 단기 보관 조건
적절한 장기 보관 조건
분주 정보
보관 정보
일반 정보
기능
E3 ubiquitin ligase that catalyzes 'Lys-63'-linked polyubiquitination of target protein, enhancing protein-protein interaction and cell signaling (PubMed : 19825828). Transfers ubiquitin from E2 ubiquitin-conjugating enzyme UBE2V1-UBE2N to substrate protein (PubMed : 19825828). Essential adapter molecule in IL17A-mediated signaling (PubMed : 19825828, PubMed : 24120361). Upon IL17A stimulation, interacts with IL17RA and IL17RC receptor chains through SEFIR domains and catalyzes 'Lys-63'-linked polyubiquitination of TRAF6, leading to TRAF6-mediated activation of NF-kappa-B and MAPkinase pathways (PubMed : 19825828).
타겟 정보
Product promise
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