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AB151334

Recombinant Human Coxsackie Adenovirus Receptor/hCAR protein

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Recombinant Human Coxsackie Adenovirus Receptor/hCAR protein is a Human Fragment protein, in the 20 to 237 aa range, expressed in HEK 293 cells, with >95%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE, HPLC.

대체 명칭 보기

CAR, CXADR, Coxsackievirus and adenovirus receptor, hCAR, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, HCVADR

주요 정보

Purity

>95% SDS-PAGE

Purtiy is greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.

Endotoxin 레벨

< 1 EU/µg

발현 시스템

HEK 293 cells

Tags

His tag C-Terminus

Applications

SDS-PAGE, HPLC

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Human

Reconstitution

Reconstitute in PBS

보관 버퍼

pH: 7.2 Constituents: 99% Phosphate Buffer, 0.88% Sodium chloride

storage-buffer

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보완 제품

Reagents, Controls & Accessories

AB234592

Prestained Protein Ladder - Extra broad molecular weight (6.5 - 270 kDa)

SDS-PAGE - Prestained Protein Ladder - Extra broad molecular weight (6.5 - 270 kDa) (AB234592)

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Proteins & Peptides

AB109148

Recombinant Human RANK protein

  • 0
  • 0
Proteins & Peptides

AB191962

Recombinant Human IL-10RB/IL-10R2 protein

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  • 0
Proteins & Peptides

AB290104

Recombinant Human Furin Protein

SDS-PAGE - Recombinant Human Furin Protein (AB290104)

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  • 0
Proteins & Peptides

AB125589

Recombinant Human IKK gamma/NEMO protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human IKK gamma/NEMO protein (AB125589)

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  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "HPLC": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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제품 세부 정보

This product was previously labelled as Coxsackie Adenovirus Receptor
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서열 정보

[{"linker":null,"sequence":"LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGVDHHHHHH","proteinLength":"Fragment","predictedMolecularWeight":"25.09 kDa","actualMolecularWeight":null,"aminoAcidEnd":237,"aminoAcidStart":20,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"P78310","tags":[{"tag":"His","terminus":"C-Terminus"}]}]
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특성 및 보관 정보

제형
Lyophilized
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
A few weeks
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
False
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일반 정보

기능

Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.. (Microbial infection) Acts as a receptor for adenovirus type C.. (Microbial infection) Acts as a receptor for Coxsackievirus B1 to B6.

Post-translational modifications

N-glycosylated.. Palmitoylated on Cys-259 and/or Cys-260; required for proper localization to the plasma membrane.

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제품 프로토콜

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타겟 정보

Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.. (Microbial infection) Acts as a receptor for adenovirus type C.. (Microbial infection) Acts as a receptor for Coxsackievirus B1 to B6.
See full target information CXADR
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Product promise

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