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AB183219

Recombinant Human DAP1 protein (His tag N-Terminus)

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Recombinant Human DAP1 protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 102 aa range, expressed in Escherichia coli, with >80%, suitable for SDS-PAGE, Mass Spec.

대체 명칭 보기

DAP1, DAP, Death-associated protein 1, DAP-1

1 이미지
SDS-PAGE - Recombinant Human DAP1 protein (His tag N-Terminus) (AB183219)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human DAP1 protein (His tag N-Terminus) (AB183219)

SDS-PAGE analysis of ab183219

주요 정보

Purity

>80% SDS-PAGE

ab183219 was purified using conventional chromatography techniques.

발현 시스템

Escherichia coli

Tags

His tag N-Terminus

Applications

Mass Spec, SDS-PAGE

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 8 Constituents: 10% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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보완 제품

Primary Antibodies

AB32056

Anti-DAP1 antibody [E59]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DAP1 antibody [E59] (AB32056)

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Primary Antibodies

AB126607

Anti-GABARAPL2/GATE-16 antibody [EP4808]

RabMAb|Recombinant|KO Validated

Western blot - Anti-GABARAPL2/GATE-16 antibody [EP4808] (AB126607)

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Assay Kits

AB176724

NADP/NADPH Assay Kit (Fluorometric)

Functional Studies - NADP/NADPH Assay Kit (Fluorometric) (AB176724)

  • 3
  • 1
Primary Antibodies

AB109364

Anti-GABARAP+GABARAPL1+GABARAPL2 antibody [EPR4805]

RabMAb|Recombinant|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GABARAP+GABARAPL1+GABARAPL2 antibody [EPR4805] (AB109364)

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"linker":null,"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMSSPPEGKLETKAGHPPAVKAGGMRIVQKHPHTGDTKEEKDKDDQEWESPSPPKPTVFISGVIARGDKDFPPAAAQVAHQKPHASMDKHPSPRTQHIQQPRK","proteinLength":"Full Length","predictedMolecularWeight":"13.6 kDa","actualMolecularWeight":null,"aminoAcidEnd":102,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P51397","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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특성 및 보관 정보

제형
Liquid
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False
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일반 정보

기능

Ribosome-binding protein involved in ribosome hibernation, a process during which ribosomes are stabilized in an inactive state and preserved from proteasomal degradation (By similarity). Acts via its association with eiF5a (EIF5A and EIF5A2) at the polypeptide exit tunnel of the ribosome, preventing mRNA translation (By similarity). Involved in ribosome hibernation in the mature oocyte by preventing mRNA translation, leading to ribosome inactivation (By similarity). Ribosomes, which are produced in large quantities during oogenesis, are stored and translationally repressed in the oocyte and early embryo (By similarity). Also acts as a negative regulator of autophagy (PubMed : 20537536). Involved in mediating interferon-gamma-induced cell death (PubMed : 7828849).

서열 유사성

Belongs to the DAP-DAPL1 family.

Post-translational modifications

Phosphorylated. Phosphorylation by MTOR inhibits the suppressive activity of DAP toward autophagy.

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제품 프로토콜

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타겟 정보

Ribosome-binding protein involved in ribosome hibernation, a process during which ribosomes are stabilized in an inactive state and preserved from proteasomal degradation (By similarity). Acts via its association with eiF5a (EIF5A and EIF5A2) at the polypeptide exit tunnel of the ribosome, preventing mRNA translation (By similarity). Involved in ribosome hibernation in the mature oocyte by preventing mRNA translation, leading to ribosome inactivation (By similarity). Ribosomes, which are produced in large quantities during oogenesis, are stored and translationally repressed in the oocyte and early embryo (By similarity). Also acts as a negative regulator of autophagy (PubMed : 20537536). Involved in mediating interferon-gamma-induced cell death (PubMed : 7828849).
See full target information DAP
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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