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AB276266

Recombinant human DcR1 protein (His tag)

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Recombinant human DcR1 protein (His tag) is a Human Fragment protein, in the 1 to 235 aa range, expressed in HEK 293 cells, with >95%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE, FuncS.

대체 명칭 보기

CD263, DCR1, LIT, TRAILR3, TRID, UNQ321/PRO366, TNFRSF10C, Tumor necrosis factor receptor superfamily member 10C, Antagonist decoy receptor for TRAIL/Apo-2L, Decoy TRAIL receptor without death domain, Decoy receptor 1, Lymphocyte inhibitor of TRAIL, TNF-related apoptosis-inducing ligand receptor 3, TRAIL receptor without an intracellular domain, DcR1, TRAIL receptor 3, TRAIL-R3

2 이미지
Functional Studies - Recombinant human DcR1 protein (His tag) (AB276266)
  • FuncS

Supplier Data

Functional Studies - Recombinant human DcR1 protein (His tag) (AB276266)

Measured by its binding ability in a functional ELISA. Immobilized human TNFRSF10C at 10 μg/mL (100 μL/well) can bind biotinylated human TNFSF10, the EC50 of biotinylated human TNFSF10 is 0.1-0.7 μg/mL.

SDS-PAGE - Recombinant human DcR1 protein (His tag) (AB276266)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant human DcR1 protein (His tag) (AB276266)

SDS-PAGE analysis of ab276266

주요 정보

Purity

>95% SDS-PAGE

Endotoxin 레벨

< 1 EU/µg

발현 시스템

HEK 293 cells

Tags

His tag C-Terminus

Applications

SDS-PAGE, FuncS

applications

Biologically active

Yes

Biological activity

Measured by its binding ability in a functional ELISA. Immobilized human TNFRSF10C at 10 μg/mL (100 μL/well) can bind biotinylated human TNFSF10, the EC50 of biotinylated human TNFSF10 is 0.1-0.7 μg/mL.

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 7.4 Constituents: PBS

storage-buffer

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보완 제품

Assay Kits

AB314710

Human DcR1 R3 ELISA Kit

Sandwich ELISA - Human DcR1 R3 ELISA Kit (AB314710)

  • 0
  • 0
Primary Antibodies

AB199320

Alexa Fluor® 488 Anti-DcR1 antibody [EPR6162]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Alexa Fluor® 488 Anti-DcR1 antibody [EPR6162] (AB199320)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"linker":null,"sequence":"MARIPKTLKFVVVIVAVLLPVLAYSATTARQEEVPQQTVAPQQQRHSFKGEECPAGSHRSEHTGACNPCTEGVDYTNASNNEPSCFPCTVCKSDQKHKSSCTMTRDTVCQCKEGTFRNENSPEMCRKCSRCPSGEVQVSNCTSWDDIQCVEEFGANATVETPAAEETMNTSPGTPAPAAEETMNTSPGTPAPAAEETMTTSPGTPAPAAEETMTTSPGTPAPAAEETMITSPGTP","proteinLength":"Fragment","predictedMolecularWeight":"23.6 kDa","actualMolecularWeight":null,"aminoAcidEnd":235,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"O14798","tags":[{"tag":"His","terminus":"C-Terminus"}]}]
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특성 및 보관 정보

제형
Lyophilized
배송 시 보관 조건
Ambient - Can Ship with Ice
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
True
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일반 정보

기능

Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.

Post-translational modifications

N-glycosylated and O-glycosylated.

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제품 프로토콜

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타겟 정보

Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
See full target information TNFRSF10C
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

EMBO reports 23:e54133 PubMed35758160

2022

Engagement of TRAIL triggers degranulation and IFNγ production in human natural killer cells.

Applications

Unspecified application

Species

Unspecified reactive species

Johannes Höfle,Timo Trenkner,Nadja Kleist,Vera Schwane,Sarah Vollmers,Bryan Barcelona,Annika Niehrs,Pia Fittje,Van Hung Huynh-Tran,Jürgen Sauter,Alexander H Schmidt,Sven Peine,Angelique Hoelzemer,Laura Richert,Marcus Altfeld,Christian Körner
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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