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AB219429

Recombinant human DCXR protein (Active) (His tag N-Terminus)

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Recombinant human DCXR protein (Active) (His tag N-Terminus) is a Human Full Length protein, in the 1 to 244 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE, FuncS, Mass Spec.

대체 명칭 보기

SDR20C1, DCXR, L-xylulose reductase, XR, Dicarbonyl/L-xylulose reductase, Kidney dicarbonyl reductase, Short chain dehydrogenase/reductase family 20C member 1, Sperm surface protein P34H, kiDCR

1 이미지
SDS-PAGE - Recombinant human DCXR protein (Active) (His tag N-Terminus) (AB219429)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant human DCXR protein (Active) (His tag N-Terminus) (AB219429)

15% SDS-PAGE analysis of 3 μg ab219429.

주요 정보

Purity

>95% SDS-PAGE

ab219429 was purified using conventional chromatography techniques.

발현 시스템

Escherichia coli

Tags

His tag N-Terminus

Applications

Mass Spec, FuncS, SDS-PAGE

applications

Biologically active

Yes

Biological activity

Specific activity is > 1,800 pmol/min/ug and is defined as the amount of enzyme that oxidize 1 pmole of xylitol to L-xylulose per minute at pH 10.0 at 37°C.

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 8 Constituents: 20% Glycerol (glycerin, glycerine), 0.32% Tris HCl, 0.29% Sodium chloride, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

서열 정보

[{"linker":null,"sequence":"MGSSHHHHHHSSGLVPRGSHMELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGGFWAC","proteinLength":"Full Length","predictedMolecularWeight":"28 kDa","actualMolecularWeight":null,"aminoAcidEnd":244,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q7Z4W1","tags":[{"tag":"His","terminus":"N-Terminus"}]}]

특성 및 보관 정보

제형
Liquid
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
True

일반 정보

기능

Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose (PubMed : 11882650, PubMed : 19337691, PubMed : 40737316). Can use both NAD and NADP as cosubstrate but shows higher activity with NADP (PubMed : 11882650). Participates in the uronate cycle of glucose metabolism (PubMed : 11882650). May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules (PubMed : 11882650).

서열 유사성

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

제품 프로토콜

타겟 정보

Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose (PubMed : 11882650, PubMed : 19337691, PubMed : 40737316). Can use both NAD and NADP as cosubstrate but shows higher activity with NADP (PubMed : 11882650). Participates in the uronate cycle of glucose metabolism (PubMed : 11882650). May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules (PubMed : 11882650).
See full target information DCXR

Product promise

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