JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB162830

Recombinant Human EPDR1 protein (GST tag N-Terminus)

Be the first to review this product! 리뷰 제출

|

(1 출판물)

Recombinant Human EPDR1 protein (GST tag N-Terminus) is a Human Full Length protein, in the 38 to 224 aa range, expressed in Wheat germ, suitable for ELISA, WB.

대체 명칭 보기

MERP1, UCC1, EPDR1, Mammalian ependymin-related protein 1, MERP-1, Upregulated in colorectal cancer gene 1 protein

1 이미지
SDS-PAGE - Recombinant Human EPDR1 protein (GST tag N-Terminus) (AB162830)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human EPDR1 protein (GST tag N-Terminus) (AB162830)

ab162830 on a 12.5% SDS-PAGE stained with Coomassie Blue.

주요 정보

발현 시스템

Wheat germ

Tags

GST tag N-Terminus

Applications

ELISA, WB

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

style
left-column

보완 제품

Primary Antibodies

AB197932

Anti-EPDR1 antibody - C-terminal

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EPDR1 antibody - C-terminal (AB197932)

  • 0
  • 0
Proteins & Peptides

AB277017

Recombinant Mouse Calnexin protein (His tag)

SDS-PAGE - Recombinant Mouse Calnexin protein (His tag) (AB277017)

  • 0
  • 0
Primary Antibodies

AB22595

Anti-Calnexin antibody - ER Marker

Lab Essentials|KO Validated

Immunocytochemistry/ Immunofluorescence - Anti-Calnexin antibody - ER Marker (AB22595)

  • 5
  • 28
Primary Antibodies

AB275377

Anti-ALIX antibody [EPR23653-32]

20ul selling size|RabMAb|Recombinant|KO Validated

Immunocytochemistry/ Immunofluorescence - Anti-ALIX antibody [EPR23653-32] (AB275377)

  • 5
  • 2
style
left-column

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
style
left-column
style
left-column

서열 정보

[{"linker":null,"sequence":"APRPCQAPQQWEGRQVMYQQSSGRNSRALLSYDGLNQRVRVLDERKALIPCKRLFEYILLYKDGVMFQIDQATKQCSKMTLTQPWDPLDIPQNSTFEDQYSIGGPQEQITVQEWSDRKSARSYETWIGIYTVKDCYPVQETFTINYSVILSTRFFDIQLGIKDPSVFTPPSTCQMAQLEKMSEDCSW","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":224,"aminoAcidStart":38,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q9UM22","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
style
left-column

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Proprietary technique
배송 시 보관 조건
Dry Ice
적절한 단기 보관 조건
-80°C
적절한 장기 보관 조건
-80°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False
style
left-column

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

EPDR1 also known as Ependymin-Related 1 is a protein involved in cellular adhesion and signaling. It has an approximate molecular mass of 55 kDa. EPDR1 is expressed in various tissues with significant levels found in the brain and also in some cancerous tissues. The protein plays a role in cellular interaction by mediating cell-cell and cell-matrix adhesion contributing to cellular cohesion and integrity.
Biological function summary

EPDR1 functions in processes of cell adhesion and immune response modulation. It may form complexes with other proteins that help regulate the structural organization of cells within tissue matrices. This modulation is essential for the repair and maintenance of tissue architecture actively influencing how cells respond to environmental changes.

Pathways

EPDR1 is significant in the ECM-receptor interaction pathway and plays a role in cell communication pathways. It interacts with other proteins like integrins which are important in mediating outside-in signaling processes. This interaction facilitates various downstream signaling events that are necessary for maintaining cell and tissue structure.

EPDR1 has been associated with cancer and neurodegenerative diseases. It may influence cancer progression through its impact on cell adhesion potentially affecting metastasis by altering cell motility and detachment. In neurological contexts the relationship with neurodegenerative diseases links to proteins like amyloid-beta where modulation by EPDR1 can affect disease progression by influencing cellular adhesion properties in neural tissues.
style
left-column

일반 정보

기능

Binds anionic lipids and gangliosides at acidic pH.

서열 유사성

Belongs to the ependymin family.

Post-translational modifications

N-glycosylated; the glycan contains mannose-6-phosphate moieties.

style
left-column

제품 프로토콜

style
left-column

타겟 정보

Binds anionic lipids and gangliosides at acidic pH.
See full target information EPDR1
style
left-column

제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Cells 11: PubMed36497009

2022

Aging Fibroblasts Adversely Affect Extracellular Matrix Formation via the Senescent Humoral Factor Ependymin-Related Protein 1.

Applications

Unspecified application

Species

Unspecified reactive species

Kento Takaya,Toru Asou,Kazuo Kishi
제품이 사용된 논문 모두 보기
style
left-column
style
left-column
style
right-column

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com