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AB165954

Recombinant Human FAM13C1 protein (GST tag N-Terminus)

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Recombinant Human FAM13C1 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 585 aa range, expressed in Wheat germ, suitable for ELISA, WB.

대체 명칭 보기

FAM13C1, FAM13C, Protein FAM13C

1 이미지
SDS-PAGE - Recombinant Human FAM13C1 protein (GST tag N-Terminus) (AB165954)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human FAM13C1 protein (GST tag N-Terminus) (AB165954)

ab165954 on a 12.5% SDS-PAGE stained with Coomassie Blue.

주요 정보

발현 시스템

Wheat germ

Tags

GST tag N-Terminus

Applications

WB, ELISA

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

서열 정보

[{"linker":null,"sequence":"MFSCFCFSLQDNSFSSTTVTECDEDPVSLHEDQTDCSSLRDENNKENYPDAGALVEEHAPPSWEPQQQNVEATVLVDSVLRHSMGNFKSRKPKSIFKAESGRSHGESQETEHVVSSQSECQVRAGTPAHESPQNNAFKCQETVRLQPRIDQRTAISPKDAFETRQDLNEEEAAQVHGVKDPAPASTQSVLADGTDSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPRCSIFSQSQRFNLDPESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRPSHGDKTSNPEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPRNLLCEQPTVPRENGKPEAAGPEPSSSGEETPDAALTCLKERREQLPPQEDSKVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLPVGDHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQDVAKTI","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":585,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q8NE31","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Proprietary technique
배송 시 보관 조건
Dry Ice
적절한 단기 보관 조건
-80°C
적절한 장기 보관 조건
-80°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

FAM13C1 also known as Family with Sequence Similarity 13 Member C1 is a protein with a molecular mass of approximately 115 kDa. This protein is primarily expressed in the pancreas and to some extent in adipose tissue. FAM13C1 resides in the cytoplasm and interacts with components of the cytoskeleton indicating a role in cellular architecture and signaling.
Biological function summary

The protein FAM13C1 is involved in regulating glucose metabolism and insulin signaling. It forms part of a dynamic protein complex that modulates the function of metabolic pathways. Research suggests it influences the activity of enzymes linked to lipid metabolism which can affect energy storage and usage in cells. This function positions FAM13C1 as an important modulator of metabolic processes.

Pathways

FAM13C1 plays a role in the insulin signaling pathway and the PI3K-Akt signaling pathway. Its function in these pathways ties it closely with proteins like PI3K and AKT which are critical for cellular growth metabolism and survival. FAM13C1’s interaction with these pathways highlights its contribution to both signaling and metabolic regulation in cells.

FAM13C1 has been associated with type 2 diabetes and obesity. Alterations in this protein's function or expression may disrupt normal insulin signaling potentially leading to insulin resistance. Such disruption links FAM13C1 with proteins like IRS1 which also play roles in insulin signaling and metabolic homeostasis. This connection highlights FAM13C1's significance in metabolic disorders.

일반 정보

서열 유사성

Belongs to the FAM13 family.

제품 프로토콜

Product promise

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