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AB167861

Recombinant Human FAM84A protein (His tag N-Terminus)

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Recombinant Human FAM84A protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 292 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.

대체 명칭 보기

FAM84A, NSE1, LRATD1, Protein LRATD1, LRAT domain-containing 1, Neurologic sensory protein 1, Protein FAM84A

1 이미지
SDS-PAGE - Recombinant Human FAM84A protein (His tag N-Terminus) (AB167861)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human FAM84A protein (His tag N-Terminus) (AB167861)

15% SDS-PAGE of 3µg ab167861.

주요 정보

Purity

>90% SDS-PAGE

ab167861 was purified using conventional chromatography techniques.

발현 시스템

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE, Mass Spec

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 8 Constituents: 10% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.32% Tris-HCl buffer, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

서열 정보

[{"linker":null,"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMGNQLDRITHLNYSELPTGDPSGIEKDELRVGVAYFFSDDEEDLDERGQPDKFGVKAPPGCTPCPESPSRHHHHLLHQLVLNETQFSAFRGQECIFSKVSGGPQGADLSVYAVTALPALCEPGDLLELLWLQPAPEPPAPAPHWAVYVGGGQIIHLHQGEIRQDSLYEAGAANVGRVVNSWYRYRPLVAELVVQNACGHLGLKSEEICWTNSESFAAWCRFGKREFKAGGEVPAGTQPPQQQYYLKVHLGENKVHTARFHSLEDLIREKRRIDASGRLRVLQELADLVDDKE","proteinLength":"Full Length","predictedMolecularWeight":"34.9 kDa","actualMolecularWeight":null,"aminoAcidEnd":292,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q96KN4","tags":[{"tag":"His","terminus":"N-Terminus"}]}]

특성 및 보관 정보

제형
Liquid
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

FAM84A also known as Family with Sequence Similarity 84 Member A is a protein that plays a role in specific mechanical functions within cells. It has a molecular mass of approximately 24 kDa. This protein is expressed in several tissues with higher expression levels seen in certain carcinoma cell lines. It is frequently found in epithelial tissues indicating its potential involvement in various cellular processes related to these locations.
Biological function summary

Research indicates that FAM84A influences cellular proliferation and migration contributing to normal cell growth and possibly carcinogenic processes. This protein does not associate with any well-defined complex but seems to perform its functions independently or in collaboration with other binding partners yet to be identified. Its role suggests that FAM84A may be important in maintaining cellular architecture and promoting cellular movement especially within epithelial environments.

Pathways

Current studies suggest that FAM84A interacts with cellular pathways associated with cell cycle progression and cancer metastasis. These pathways regulate cell division and expansion contributing to the spread of cancerous cells. FAM84A also shows potential associations with signaling molecules that manage cell motility such as cadherins although direct links in these pathways need more exploration.

FAM84A has been linked to cancer particularly colorectal cancer and prostate cancer. Its upregulation correlates with tumor aggressiveness highlighting its potential as a biomarker for these malignancies. FAM84A also shows interactions with proteins such as p53 which is central to the regulation of cell cycle and apoptosis further supporting its relevance in cancer pathophysiology. Understanding these associations helps in exploring therapeutic approaches targeting FAM84A in certain cancers.

일반 정보

기능

May play a role in cell morphology and motility.

서열 유사성

Belongs to the LRATD family.

제품 프로토콜

타겟 정보

May play a role in cell morphology and motility.
See full target information LRATD1

Product promise

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