Recombinant Human Filaggrin protein (His tag) is a Human Fragment protein, in the 3838 to 4061 aa range, expressed in Yeast, with >90%, suitable for SDS-PAGE.
대체 명칭 보기
Filaggrin, FLG
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human Filaggrin protein (His tag) (AB240777)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel analysis of ab240777.
보완 제품
Primary Antibodies
AB221155
Anti-Filaggrin antibody [EPR21892]
BOND RX™ Validated|20ul selling size|Recombinant|Advanced Validation|RabMAb
![Multiplex immunohistochemistry - Anti-Filaggrin antibody [EPR21892] (AB221155)](https://content.abcam.com/products/images/filaggrin-antibody-epr21892-ab221155--multiplex-immunohistochemistry-img464148.jpg)
- 5
- 3
Reactivity 정보
서열 정보
특성 및 보관 정보
제형
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적절한 단기 보관 조건
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보관 정보
일반 정보
기능
Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis.
서열 유사성
Belongs to the S100-fused protein family.
Post-translational modifications
Filaggrin is initially synthesized as a large, insoluble, highly phosphorylated precursor containing many tandem copies of 324 AA, which are not separated by large linker sequences. During terminal differentiation it is dephosphorylated and proteolytically cleaved. The N-terminal of the mature protein is heterogeneous, and is blocked by the formation of pyroglutamate.. Undergoes deimination of some arginine residues (citrullination).
타겟 정보
Product promise
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