Recombinant Human GAA protein (GST tag N-Terminus)
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Recombinant Human GAA protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 952 aa range, expressed in Wheat germ, with >80%, suitable for SDS-PAGE, ELISA, WB.
대체 명칭 보기
Lysosomal alpha-glucosidase, Acid maltase, Aglucosidase alfa, GAA
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human GAA protein (GST tag N-Terminus) (AB114893)
12.5% SDS-PAGE showing ab114893 at approximately 130.79kDa.
Stained with Coomassie Blue.
Reactivity 정보
서열 정보
특성 및 보관 정보
제형
Purification 테크닉
배송 시 보관 조건
적절한 단기 보관 조건
적절한 장기 보관 조건
분주 정보
보관 정보
일반 정보
기능
Essential for the degradation of glycogen in lysosomes (PubMed : 14695532, PubMed : 18429042, PubMed : 1856189, PubMed : 7717400). Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans (PubMed : 29061980).
서열 유사성
Belongs to the glycosyl hydrolase 31 family.
Post-translational modifications
The different forms of acid glucosidase are obtained by proteolytic processing.. Phosphorylation of mannose residues ensures efficient transport of the enzyme to the lysosomes via the mannose 6-phosphate receptor.
Subcellular localisation
Lysosome
타겟 정보
Product promise
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