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AB107951

Recombinant Human Galectin 10 protein (His tag N-Terminus)

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Recombinant Human Galectin 10 protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 162 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.
1 이미지
SDS-PAGE - Recombinant Human Galectin 10 protein (His tag N-Terminus) (AB107951)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human Galectin 10 protein (His tag N-Terminus) (AB107951)

15% SDS-PAGE analysis of ab107951 (3 µg).

주요 정보

Purity

>90% SDS-PAGE

Purified using conventional chromatography techniques.

발현 시스템

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE, Mass Spec

applications

Biologically active

No

Accession

Q05315-1

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 8 Constituents: 10% Glycerol (glycerin, glycerine), 0.58% Sodium chloride, 0.316% Tris HCl, 0.0154% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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보완 제품

Reagents, Controls & Accessories

AB325994

Prestained Protein Ladder - Mid-range molecular weight (11-180 kDa, 4-color)

SDS-PAGE - Prestained Protein Ladder - Mid-range molecular weight (11-180 kDa, 4-color) (AB325994)

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Proteins & Peptides

AB99294

Recombinant Human Galectin 8/Gal-8 protein (His tag N-Terminus)

Western blot - Recombinant Human Galectin 8/Gal-8 protein (His tag N-Terminus) (AB99294)

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  • 0
Reagents, Controls & Accessories

AB7475

Normal Donkey Serum

Immunohistochemistry (PFA perfusion fixed frozen sections) - Normal Donkey Serum (AB7475)

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Primary Antibodies

AB77230

APC Anti-CD177 antibody [MEM-166]

Flow Cytometry - APC Anti-CD177 antibody [MEM-166] (AB77230)

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Proteins & Peptides

AB99239

Recombinant Human Galectin 2 protein (His tag N-Terminus)

SDS-PAGE - Recombinant Human Galectin 2 protein (His tag N-Terminus) (AB99239)

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  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"linker":null,"sequence":"MGSSHHHHHHSSGLVPRGSHMSLLPVPYTEAASLSTGSTVTIKGRPLACFLNEPYLQVDFHTEMKEESDIVFHFQVCFGRRVVMNSREYGAWKQQVESKNMPFQDGQEFELSISVLPDKYQVMVNGQSSYTFDHRIKPEAVKMVQVWRDISLTKFNVSYLKR","proteinLength":"Full Length","predictedMolecularWeight":"18.6 kDa","actualMolecularWeight":null,"aminoAcidEnd":162,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q05315","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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특성 및 보관 정보

제형
Liquid
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Galectin-10 also known as Charcot-Leyden crystal protein is part of the galectin family of proteins. It functions by binding to carbohydrates due to its unique lectin properties. With a molecular mass of approximately 16.5 kDa this protein is mainly expressed in eosinophils and basophils cells that are significant in the immune system. Galectin-10 is secreted by these cells and also stored in their granules suggesting its importance in immune responses.
Biological function summary

Galectin-10 influences cellular processes like apoptosis cell adhesion and immune cell migration contributing to immune regulation. It is not well known to form part of large complexes but its release has implications on cell signaling and tissue remodeling. The presence of galectin-10 in eosinophils suggests a role in inflammation given their involvement in allergic responses and asthma.

Pathways

Studies associate galectin-10 with the allergy response and eosinophil apoptosis pathways. This protein cooperates with other galectin family members like galectin-3 in modulating cellular responses. Signaling interactions of galectin-10 impact pathways involving cell survival and death highlighting its role in immune system dynamics.

Researchers link galectin-10 to conditions such as asthma and eosinophilic disorders. Eosinophil activity in these diseases often correlates with elevated galectin-10 levels in tissues and bloodstream. Connections exist between galectin-10 and other inflammation-related proteins like interleukins influencing disease progression and severity through their regulatory roles in immune responses.
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제품 프로토콜

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타겟 정보

Regulates immune responses through the recognition of cell-surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg).
See full target information CLC

대체 명칭 보기

LGALS10, LGALS10A, CLC, Galectin-10, Gal-10, Charcot-Leyden crystal protein, Eosinophil lysophospholipase, Lysolecithin acylhydrolase
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록and refine your search

Nature communications 14:5291 PubMed37652913

2023

Antibody-mediated neutralization of galectin-3 as a strategy for the treatment of systemic sclerosis.

Applications

Unspecified application

Species

Unspecified reactive species

Céline Ortega-Ferreira,Perrine Soret,Gautier Robin,Silvia Speca,Sandra Hubert,Marianne Le Gall,Emiko Desvaux,Manel Jendoubi,Julie Saint-Paul,Loubna Chadli,Agnès Chomel,Sylvie Berger,Emmanuel Nony,Béatrice Neau,Benjamin Fould,Anne Licznar,Franck Levasseur,Thomas Guerrier,Sahar Elouej,Sophie Courtade-Gaïani,Nicolas Provost,The Quyen Nguyen,Julien Verdier,David Launay,Frédéric De Ceuninck
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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