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AB256090

Recombinant human GDF8 / Myostatin protein (Animal Free)

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Recombinant human GDF8 / Myostatin protein (Animal Free) is a Human Full Length protein, in the 267 to 375 aa range, expressed in Escherichia coli, with >95%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE, FuncS.

대체 명칭 보기

GDF8, MSTN, Growth/differentiation factor 8, GDF-8, Myostatin

2 이미지
Functional Studies - Recombinant human GDF8 / Myostatin protein (Animal Free) (AB256090)
  • FuncS

Supplier Data

Functional Studies - Recombinant human GDF8 / Myostatin protein (Animal Free) (AB256090)

Functional analysis of ab256090.

Peptide Array - Recombinant human GDF8 / Myostatin protein (Animal Free) (AB256090)
  • PepArr

Supplier Data

Peptide Array - Recombinant human GDF8 / Myostatin protein (Animal Free) (AB256090)

SDS-PAGE analysis of ab256090 (1 μg) under non-reducing (Lane 1) and reducing (Lane 2) conditions. ab256090 is a homodimer with a predicted MW of 24.8 kDa (monomer size is 12.4 kDa).

4-20% Tris-Glycine gel. Coomassie Blue staining.

주요 정보

Purity

>95% SDS-PAGE

Endotoxin 레벨

< 1 EU/µg

발현 시스템

Escherichia coli

Tags

Tag free

Applications

FuncS, SDS-PAGE

applications

Biologically active

Yes

Biological activity

MPC-11 cell cytotoxicity. ≤50 ng/ml; ≥ 2.0 x 104 units/mg.

Accession

Animal free

Yes

Carrier free

Yes

Species

Human

Reconstitution

Reconstitute at 0.1 mg/mL in 20 mM HCl. Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution.

보관 버퍼

Constituents: 0.1% Trifluoroacetic acid

storage-buffer

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보완 제품

Reagents, Controls & Accessories

AB234617

Prestained Protein Ladder - Mid-range molecular weight (10 - 180 kDa)

SDS-PAGE - Prestained Protein Ladder - Mid-range molecular weight (10 - 180 kDa) (AB234617)

  • 0
  • 0
Secondary Antibodies

AB205718

Goat Anti-Rabbit IgG H&L (HRP)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Goat Anti-Rabbit IgG H&L (HRP) (AB205718)

  • 5
  • 8
Primary Antibodies

AB201954

Anti-GDF8 / Myostatin antibody [6E4B2]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GDF8 / Myostatin antibody [6E4B2] (AB201954)

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  • 0
Secondary Antibodies

AB205719

Goat Anti-Mouse IgG H&L (HRP)

Western blot - Goat Anti-Mouse IgG H&L (HRP) (AB205719)

  • 5
  • 4
Proteins & Peptides

AB218080

Recombinant human GDF11 protein (Active)

Functional Studies - Recombinant human GDF11 protein (Active) (AB218080)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"linker":null,"sequence":"DFGLDCDEHSTESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGECEFVFLQKYPHTHLVHQANPRGSAGPCCTPTKMSPINMLYFNGKEQIIYGKIPAMVVDRCGCS","proteinLength":"Full Length","predictedMolecularWeight":"12.4 kDa","actualMolecularWeight":null,"aminoAcidEnd":375,"aminoAcidStart":267,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"O14793","tags":[]}]
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특성 및 보관 정보

제형
Lyophilized
배송 시 보관 조건
Ambient - Can Ship with Ice
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot|Upon reconstitution add a carrier protein (0.1% BSA)
보관 정보
Avoid freeze / thaw cycle|Working aliquots stored with a carrier protein are stable for at least 3 months at -20°C to -80°C.
True
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일반 정보

기능

Acts specifically as a negative regulator of skeletal muscle growth.

서열 유사성

Belongs to the TGF-beta family.

Post-translational modifications

Synthesized as large precursor molecule that undergoes proteolytic cleavage to generate an N-terminal propeptide and a disulfide linked C-terminal dimer, which is the biologically active molecule. The circulating form consists of a latent complex of the C-terminal dimer and other proteins, including its propeptide, which maintain the C-terminal dimer in a latent, inactive state. Ligand activation requires additional cleavage of the prodomain by a tolloid-like metalloproteinase.

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제품 프로토콜

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타겟 정보

Acts specifically as a negative regulator of skeletal muscle growth.
See full target information MSTN
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Nature communications 16:5976 PubMed40593645

2025

Molecular mechanism of Activin receptor inhibition by DLK1.

Applications

Unspecified application

Species

Unspecified reactive species

Daniel Antfolk,Qianqian Ming,Anna Manturova,Erich J Goebel,Thomas B Thompson,Vincent C Luca
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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