JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB268603

Recombinant Human GNAZ protein (GST tag N-Terminus)

Be the first to review this product! 리뷰 제출

|

(0 출판물)

Recombinant Human GNAZ protein (GST tag N-Terminus) is a Human Full Length protein, in the 2 to 355 aa range, expressed in Escherichia coli, with >70%, suitable for SDS-PAGE.

대체 명칭 보기

Guanine nucleotide-binding protein G(z) subunit alpha, G(x) alpha chain, Gz-alpha, GNAZ

1 이미지
SDS-PAGE - Recombinant Human GNAZ protein (Tagged) (AB268603)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human GNAZ protein (Tagged) (AB268603)

SDS-PAGE analysis of ab268603.

MW ~65 kDa.

주요 정보

Purity

>70% SDS-PAGE

발현 시스템

Escherichia coli

Tags

GST tag N-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 7.5 Constituents: 25% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, 0.79% Tris HCl, 0.31% Glutathione, 0.004% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.003% EDTA, 0.002% PMSF

storage-buffer

style
left-column

보완 제품

Primary Antibodies

AB154846

Anti-GNAZ antibody [EPR8654]

RabMAb|Recombinant

Western blot - Anti-GNAZ antibody [EPR8654] (AB154846)

  • 0
  • 0
style
left-column

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
style
left-column
style
left-column

서열 정보

[{"linker":null,"sequence":"GCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKEYKPLIIYNAIDSLTRIIRALAALRIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFSRSSEYHLEDNAAYYLNDLERIAAADYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLTICFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":355,"aminoAcidStart":2,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P19086","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
style
left-column

특성 및 보관 정보

제형
Liquid
배송 시 보관 조건
Dry Ice
적절한 단기 보관 조건
-80°C
적절한 장기 보관 조건
-80°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False
style
left-column

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

GNAZ also known as Guanine nucleotide-binding protein G(z) subunit alpha functions as a modulator or transducer in various transmembrane signaling systems. The protein plays an essential role in coupling cell surface receptors to intracellular signaling pathways. GNAZ weighs approximately 41.5 kDa and is widely expressed in human brain tissues and certain neuroendocrine tissues.
Biological function summary

GNAZ connects with receptor-mediated signal transduction aiding in neurotransmitter release and sensory perception. GNAZ functions as part of the heterotrimeric G-protein complex which includes G beta and G gamma subunits. This protein often regulates signal transduction cascades that influence cellular responses to external stimuli.

Pathways

GNAZ is closely linked to important signaling pathways such as the serotonergic signaling pathway and the phototransduction pathway. Within these pathways GNAZ interacts with kinases and ion channels influencing cellular responses and synaptic functions. GNAZ works alongside related proteins such as GNAI and GNAT contributing to the regulation of neurotransmitter systems.

GNAZ relates to neurological disorders and certain psychiatric conditions including schizophrenia and bipolar disorder. Changes in the activity or expression of GNAZ may impact neurotransmitter systems which are fundamental to these conditions. Through these disorders GNAZ connects with proteins like GNB and GNG pointing to its involvement in signal processing abnormalities that underlie these diseases.
style
left-column

일반 정보

기능

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

서열 유사성

Belongs to the G-alpha family. G(i/o/t/z) subfamily.

style
left-column

제품 프로토콜

style
left-column

타겟 정보

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
See full target information Guanine nucleotide-binding protein G(z) subunit alpha
style
left-column
style
left-column
style
right-column

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com