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AB156974

Recombinant Human GOLGA7 protein (His tag N-Terminus)

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Recombinant Human GOLGA7 protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 137 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.

대체 명칭 보기

GCP16, HDCKB03P, HSPC041, GOLGA7, Golgin subfamily A member 7, Golgi complex-associated protein of 16 kDa

1 이미지
SDS-PAGE - Recombinant Human GOLGA7 protein (His tag N-Terminus) (AB156974)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human GOLGA7 protein (His tag N-Terminus) (AB156974)

15% SDS-PAGE analysis of ab156974 (3µg).

주요 정보

Purity

>90% SDS-PAGE

ab156974 is purified using conventional chromatography techniques.

발현 시스템

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE, Mass Spec

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 8 Constituents: 30% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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보완 제품

Proteins & Peptides

AB156977

Recombinant Human Galanin protein (His tag N-Terminus)

SDS-PAGE - Recombinant Human Galanin protein (His tag N-Terminus) (AB156977)

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Primary Antibodies

AB316860

Anti-EBV Nuclear Antigen/EBNA1 antibody [EPR28706-78]

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EBV Nuclear Antigen/EBNA1 antibody [EPR28706-78] (AB316860)

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  • 0
Primary Antibodies

AB205581

Anti-IGFBP4 antibody [EPR19762]

RabMAb|Recombinant

Flow Cytometry (Intracellular) - Anti-IGFBP4 antibody [EPR19762] (AB205581)

  • 0
  • 0
Proteins & Peptides

AB138345

Recombinant EBV Nuclear Antigen/EBNA1 protein

  • 5
  • 1
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"linker":null,"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMRPQQAPVSGKVFIQRDYSSGTRCQFQTKFPAELENRIDRQQFEETVRTLNNLYAEAEKLGGQSYLEGCLACLTAYTIFLCMETHYEKVLKKVSKYIQEQNEKIYAPQGLLLTDPIERGLRVIEITIYEDRGMSSGR","proteinLength":"Full Length","predictedMolecularWeight":"18 kDa","actualMolecularWeight":null,"aminoAcidEnd":137,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q7Z5G4","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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특성 및 보관 정보

제형
Liquid
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

GOLGA7 also known as Golgi autoantigen is a small protein with a mass of approximately 15 kDa. It is expressed in a wide variety of tissues with notable expression in the Golgi apparatus where it plays a role in maintaining its structure and function. GOLGA7 participates in membrane trafficking within the Golgi by contributing to the organization and stabilization of the Golgi architecture.
Biological function summary

This protein assists in the formation and maintenance of the Golgi ribbon a structure necessary for proper cellular function. GOLGA7 associates with GOLGA7B forming a complex that facilitates interaction with other Golgi-resident proteins. This interaction supports the precise cargo transport processes that are essential for cellular homeostasis. The protein’s role within the complex highlights its essential position in cellular logistics.

Pathways

The involvement of GOLGA7 in the Golgi apparatus influences membrane trafficking pathways. It plays a significant role in the vesicle-mediated transport process and interacts with proteins such as ZDHHC9 within these pathways. These interactions are important for the correct localization and function of transported proteins impacting processes like signal transduction and protein glycosylation.

GOLGA7 has been implicated in conditions like cancer and congenital disorders of glycosylation. Changes in GOLGA7 expression or function can lead to disruptions in normal cellular transport processes contributing to disease pathogenesis. Additionally its interaction with proteins such as RAS can influence oncogenic pathways linking it to tumorigenesis. Understanding these connections can aid in developing targeted therapies for related conditions.
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일반 정보

기능

May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS.

서열 유사성

Belongs to the ERF4 family.

Post-translational modifications

Palmitoylated on Cys-69 and Cys-72; which is required for Golgi localization and interaction with GOLGA3.

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제품 프로토콜

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타겟 정보

May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS.
See full target information GOLGA7
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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