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AB162723

Recombinant Human GPCR GPR85 protein (GST tag N-Terminus)

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Recombinant Human GPCR GPR85 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 370 aa range, expressed in Wheat germ, suitable for ELISA, WB.

대체 명칭 보기

SREB2, GPR85, Probable G-protein coupled receptor 85, Super conserved receptor expressed in brain 2

1 이미지
SDS-PAGE - Recombinant Human GPCR GPR85 protein (GST tag N-Terminus) (AB162723)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human GPCR GPR85 protein (GST tag N-Terminus) (AB162723)

ab162723 on a 12.5% SDS-PAGE stained with Coomassie Blue.

주요 정보

발현 시스템

Wheat germ

Tags

GST tag N-Terminus

Applications

WB, ELISA

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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보완 제품

Reagents, Controls & Accessories

AB325995

Prestained Protein Ladder - Broad molecular weight (11-250 kDa, 5-color, 11 bands)

SDS-PAGE - Prestained Protein Ladder - Broad molecular weight (11-250 kDa, 5-color, 11 bands) (AB325995)

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Primary Antibodies

AB140783

Anti-GPCR GPR85 antibody - Extracellular domain

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GPCR GPR85 antibody - Extracellular domain (AB140783)

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Proteins & Peptides

AB162109

Recombinant Human VPS4a protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human VPS4a protein (GST tag N-Terminus) (AB162109)

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Proteins & Peptides

AB186079

Recombinant Human TRIB1 protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human TRIB1 protein (AB186079)

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Proteins & Peptides

AB186094

Recombinant Human TRIB2 protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human TRIB2 protein (AB186094)

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  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"linker":null,"sequence":"MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCAFQHRSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKSRLPREPYCVI","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":370,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"P60893","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Proprietary technique
배송 시 보관 조건
Dry Ice
적절한 단기 보관 조건
-80°C
적절한 장기 보관 조건
-80°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

The GPCR GPR85 also known as Super Conserved Receptor Expressed in the Brain 2 (SREB2) is a G-protein coupled receptor. It weighs approximately 43 kilodaltons. GPR85 is mostly expressed in the central nervous system especially in areas such as the cerebral cortex and hippocampus. The structure of GPCRs including GPR85 enables these receptors to extend across the cell membrane seven times which allows them to transmit signals from extracellular space into the cell.
Biological function summary

GPR85 plays a role in modulating neuronal signal transduction. It is part of the family of GPCRs that connects external signal molecules to internal cellular responses. Though GPR85 does not form multi-protein complexes often it influences neuronal functions and developmental processes. Its signaling can affect neurotransmitter release impacting brain function and neural connectivity.

Pathways

Researchers place GPR85 in pathways related to neurodevelopment and synaptic transmission. GPR85 involves itself in the GPCR signaling pathway and neuroactive ligand-receptor interaction path. It relates to proteins like GPR84 and other GPCRs sharing signaling mechanisms that influence brain physiology. GPR85 can carry out vital functions that connect extracellular signals with intracellular activities important for neuronal health.

Scientists associate GPR85 with schizophrenia and cognitive disorders. Alterations in GPR85 expression or function may contribute to these conditions potentially disrupting normal neural signaling and connectivity. GPR85 might interact with proteins such as GPR88 which are also involved in cognitive functions suggesting a complex network of GPCRs in maintaining proper mental health. Understanding these interactions helps in developing therapeutic approaches for brain-related disorders.
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일반 정보

기능

Orphan receptor.

서열 유사성

Belongs to the G-protein coupled receptor 1 family.

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제품 프로토콜

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타겟 정보

Orphan receptor.
See full target information GPR85
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Product promise

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