JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB314629

Recombinant Human GPR157 Protein (His Tag)

Be the first to review this product! 리뷰 제출

|

(0 출판물)

Recombinant Human GPR157 Protein (His Tag) is a Human Full Length protein, in the 1 to 335 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE.

대체 명칭 보기

G-protein coupled receptor 157, GPR157

1 이미지
SDS-PAGE - Recombinant Human GPR157 Protein (His Tag) (AB314629)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human GPR157 Protein (His Tag) (AB314629)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

주요 정보

Purity

>85% SDS-PAGE

발현 시스템

Escherichia coli

Tags

10x His tag N-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Animal free

Yes

Carrier free

No

Species

Human

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%.

보관 버퍼

pH: 7.4 - 8 Constituents: PBS, 6% Trehalose

storage-buffer

style
left-column

보완 제품

Proteins & Peptides

AB160463

Recombinant Human Neurexin 1 protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human Neurexin 1 protein (GST tag N-Terminus) (AB160463)

  • 0
  • 0
Proteins & Peptides

AB151351

Recombinant Human Angiogenin protein

  • 0
  • 0
Assay Kits

AB110217

MitoBiogenesis™ In-Cell ELISA Kit (Colorimetric)

In-Cell ELISA - MitoBiogenesis™ In-Cell ELISA Kit (Colorimetric) (AB110217)

  • 5
  • 2
Primary Antibodies

AB33279

FITC Anti-P-Selectin (CD62P) antibody [AK-6]

  • 0
  • 0
style
left-column

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
style
left-column
style
left-column

서열 정보

[{"linker":null,"sequence":"MQPSPPPTELVPSERAVVLLSCALSALGSGLLVATHALWPDLRSRARRLLLFLSLADLLSAASYFYGVLQNFAGPSWDCVLQGALSTFANTSSFFWTVAIALYLYLSIVRAARGPRTDRLLWAFHVVSWGVPLVITVAAVALKKIGYDASDVSVGWCWIDLEAKDHVLWMLLTGKLWEMLAYVLLPLLYLLVRKHINRAHTALSEYRPILSQEHRLLRHSSMADKKLVLIPLIFIGLRVWSTVRFVLTLCGSPAVQTPVLVVLHGIGNTFQGGANCIMFVLCTRAVRTRLFSLCCCCCSSQPPTKSPAGTPKAPAPSKPGESQESQGTPGELPST","proteinLength":"Full Length","predictedMolecularWeight":"39.4 kDa","actualMolecularWeight":null,"aminoAcidEnd":335,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q5UAW9","tags":[{"tag":"10x His","terminus":"N-Terminus"}]}]
style
left-column

특성 및 보관 정보

제형
Lyophilized
Purification 테크닉
Ion exchange chromatography
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-80°C
분주 정보
Add glycerol to a final volume of 50% for extra stability and aliquot
보관 정보
The product can be stored for up to 12 months
False
style
left-column

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

G protein-coupled receptor 157 also known as GPR157 is a member of the GPCR family involved in cell signaling. This protein has a significant role in signal transmission across cell membranes. The molecular mass of GPR157 is approximately 38 kDa. GPR157 is expressed in a variety of tissues with notable expression within the brain indicating its involvement in neurological processes.
Biological function summary

GPR157 influences various processes by modulating intracellular signaling pathways. It participates in forming complexes with other cellular proteins contributing to significant biological activities. The protein is known for its role in neural development and function. It interacts with other receptors and signaling molecules within the cell to regulate brain-related mechanisms showing its importance in neurobiology.

Pathways

GPR157 plays a critical role in the Wnt signaling pathway and the neurotrophic factor-mediated pathway. Through these pathways GPR157 interacts with other proteins like β-catenin and TrkB which are important for signal transduction related to cell growth and survival. This involvement highlights its significance in maintaining normal cellular processes and preventing abnormal signaling.

GPR157 has implications in neurological conditions and psychiatric disorders notably schizophrenia and neurodegenerative diseases. There are associations between GPR157 and dysregulated signaling processes involving proteins like dopamine receptors which could lead to improper brain functioning. Studying GPR157 provides insights into potential therapeutic targets for these conditions.
style
left-column

일반 정보

기능

Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger.

서열 유사성

Belongs to the G-protein coupled receptor 2 family.

style
left-column

제품 프로토콜

style
left-column

타겟 정보

Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger.
See full target information human G-protein coupled receptor 157
style
left-column
style
left-column
style
right-column

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com