Recombinant Human HAPLN1 protein (His tag) is a Human Full Length protein, in the 1 to 354 aa range, expressed in HEK 293 cells, with >90%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.
대체 명칭 보기
CRTL1, HAPLN1, Hyaluronan and proteoglycan link protein 1, Cartilage-linking protein 1, Proteoglycan link protein, Cartilage-link protein
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human HAPLN1 protein (His tag) (AB276245)
SDS-PAGE analysis of ab276245.
As a result of glycosylation, it migrates with a molecular mass of approximately 52 kDa in SDS-PAGE under reducing conditions.
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This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Hyaluronan and proteoglycan link protein 1 supports the organization and stabilization of the extracellular matrix network. As part of this framework HAPLN1 forms complexes with hyaluronan and aggrecan ensuring structural stability and resilience in tissues experiencing mechanical stress. The association with such complexes impacts cellular signaling and tissue hydration which are important for maintaining tissue homeostasis and function.
Pathways
HAPLN1 participates in extracellular matrix organization and cell signaling processes. It is actively involved in the aggrecan pathway which influences cartilage development and repair. HAPLN1 is also connected to proteins like aggrecan and link proteins that help mediate interactions within the matrix and regulate cellular responses to mechanical stress.
일반 정보
기능
Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix.
서열 유사성
Belongs to the HAPLN family.
타겟 정보
Product promise
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