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AB114831

Recombinant Human IL-15RA protein (GST tag N-Terminus)

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Recombinant Human IL-15RA protein (GST tag N-Terminus) is a Human Fragment protein, in the 31 to 130 aa range, expressed in Wheat germ, suitable for SDS-PAGE, ELISA, WB.

대체 명칭 보기

CD215, Interleukin-15 receptor subunit alpha, IL-15 receptor subunit alpha, IL-15R-alpha, IL-15RA, IL15RA

1 이미지
SDS-PAGE - Recombinant Human IL-15RA protein (GST tag N-Terminus) (AB114831)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human IL-15RA protein (GST tag N-Terminus) (AB114831)

ab114831 analyzed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

주요 정보

발현 시스템

Wheat germ

Tags

GST tag N-Terminus

Applications

ELISA, SDS-PAGE, WB

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 8 Constituents: 0.79% Tris HCl, 0.3% Glutathione

storage-buffer

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보완 제품

Assay Kits

AB264618

Human IL-15RA ELISA Kit

Recombinant|SimpleStep

Sandwich ELISA - Human IL-15RA ELISA Kit (AB264618)

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Primary Antibodies

AB273022

Anti-IL-15RA antibody [EPR24784-142]

BOND RX™ Validated|20ul selling size|RabMAb|Recombinant

Flow Cytometry - Anti-IL-15RA antibody [EPR24784-142] (AB273022)

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Proteins & Peptides

AB318252

Recombinant human IL36 gamma/IL-1F9 protein (His Tag)

Mass Spectrometry - Recombinant human IL36 gamma/IL-1F9 protein (His Tag) (AB318252)

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Assay Kits

AB270218

Human IL-7 ELISA Kit

Recombinant|SimpleStep

ELISA - Human IL-7 ELISA Kit (AB270218)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p>(Recombinant protein).</p>" } } }
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서열 정보

[{"linker":null,"sequence":"ITCPPPMSVEHADIWVKSYSLYSRERYICNSGFKRKAGTSSLTECVLNKATNVAHWTTPSLKCIRDPALVHQRPAPPSTVTTAGVTPQPESLSPSGKEPA","proteinLength":"Fragment","predictedMolecularWeight":"36.63 kDa","actualMolecularWeight":null,"aminoAcidEnd":130,"aminoAcidStart":31,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q13261","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Proprietary technique
배송 시 보관 조건
Dry Ice
적절한 단기 보관 조건
-80°C
적절한 장기 보관 조건
-80°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False
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일반 정보

기능

High-affinity receptor for interleukin-15 (PubMed : 8530383). Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells (By similarity). In neutrophils, binds and activates kinase SYK in response to IL15 stimulation (PubMed : 15123770). In neutrophils, required for IL15-induced phagocytosis in a SYK-dependent manner (PubMed : 15123770). Expression of different isoforms may alter or interfere with signal transduction (PubMed : 10480910).. Isoform 5. Does not bind IL15.. Isoform 6. Does not bind IL15.. Isoform 7. Does not bind IL15.. Isoform 8. Does not bind IL15.

Post-translational modifications

N-glycosylated and O-glycosylated.. A soluble form (sIL-15RA) arises from proteolytic shedding of the membrane-anchored receptor (PubMed:15265897). It also binds IL-15 and thus interferes with IL-15 binding to the membrane receptor (PubMed:15265897).

Subcellular localisation

Nucleus membrane

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제품 프로토콜

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타겟 정보

High-affinity receptor for interleukin-15 (PubMed : 8530383). Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells (By similarity). In neutrophils, binds and activates kinase SYK in response to IL15 stimulation (PubMed : 15123770). In neutrophils, required for IL15-induced phagocytosis in a SYK-dependent manner (PubMed : 15123770). Expression of different isoforms may alter or interfere with signal transduction (PubMed : 10480910).. Isoform 5. Does not bind IL15.. Isoform 6. Does not bind IL15.. Isoform 7. Does not bind IL15.. Isoform 8. Does not bind IL15.
See full target information IL15RA
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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