Recombinant Human IL-17C protein (GST tag N-Terminus)
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Recombinant Human IL-17C protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 197 aa range, expressed in Wheat germ, suitable for ELISA, WB.
대체 명칭 보기
UNQ561/PRO1122, IL17C, Interleukin-17C, IL-17C, Cytokine CX2
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human IL-17C protein (GST tag N-Terminus) (AB162110)
ab162110 on a 12.5% SDS-PAGE stained with Coomassie Blue.
Reactivity 정보
서열 정보
특성 및 보관 정보
제형
Purification 테크닉
배송 시 보관 조건
적절한 단기 보관 조건
적절한 장기 보관 조건
분주 정보
보관 정보
일반 정보
기능
Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and pro-inflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes. Depending on the type of insult, may have both protective and pathogenic properties, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases.
서열 유사성
Belongs to the IL-17 family.
타겟 정보
Product promise
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