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AB179621

Recombinant human IL-21 protein (Animal Free)

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Recombinant human IL-21 protein (Animal Free) is a Human Full Length protein, in the 25 to 155 aa range, expressed in Escherichia coli, with >95%, <1 EU/µg endotoxin level, suitable for SDS-PAGE, FuncS.

대체 명칭 보기

Interleukin-21, IL-21, Za11, IL21

2 이미지
Functional Studies - Recombinant human IL-21 protein (Animal Free) (AB179621)
  • FuncS

Unknown

Functional Studies - Recombinant human IL-21 protein (Animal Free) (AB179621)

Functional analysis of ab179621

SDS-PAGE - Recombinant human IL-21 protein (Animal Free) (AB179621)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant human IL-21 protein (Animal Free) (AB179621)

SDS PAGE analysis of ab179621 under non-reducing (-) and reducing (+) conditions. Stained with Coomassie Blue.

주요 정보

Purity

>95% SDS-PAGE

The purity of ab179621 was determined using reducing and non-reducing SDS-PAGE, UV spectroscopy at 280 nm.

Endotoxin 레벨

<1 EU/µg

발현 시스템

Escherichia coli

Tags

Tag free

Applications

SDS-PAGE, FuncS

applications

Biologically active

Yes

Biological activity

B9 cell proliferation: ED50 ≤50ng/ml; ≥ 2.0 x 104 units/mg.

Accession

Animal free

Yes

Carrier free

Yes

Species

Human

Reconstitution

Reconstitute at 0.1 mg/mL in water

보관 버퍼

Constituents: 0.28% Sodium phosphate

storage-buffer

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

서열 정보

[{"linker":null,"sequence":"MQDRHMIRMRQLIDIVDQLKNYVNDLVPEFLPAPEDVETNCEWSAFSCFQKAQLKSANTGNNERIINVSIKKLKRKPPSTNAGRRQKHRLTCPSCDSYEKKPPKEFLERFKSLLQKMIHQHLSSRTHGSEDS","proteinLength":"Full Length","predictedMolecularWeight":"15.5 kDa","actualMolecularWeight":null,"aminoAcidEnd":155,"aminoAcidStart":25,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q9HBE4","tags":[]}]

특성 및 보관 정보

제형
Lyophilized
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
For long term storage it is recommended to add a carrier protein on reconstitution (0.1% HSA or BSA)
True

일반 정보

기능

Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells (PubMed : 11081504, PubMed : 15178704). During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation (By similarity).

서열 유사성

Belongs to the IL-15/IL-21 family.

제품 프로토콜

타겟 정보

Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells (PubMed : 11081504, PubMed : 15178704). During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation (By similarity).
See full target information IL21

Product promise

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