Recombinant human IL-21 protein (His tag C-Terminus)
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Recombinant human IL-21 protein (His tag C-Terminus) is a Human Full Length protein, in the 23 to 155 aa range, expressed in Baculovirus infected insect cells, with >85%, < 1 EU/µL endotoxin level, suitable for SDS-PAGE, FuncS.
대체 명칭 보기
Interleukin-21, IL-21, Za11, IL21
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant human IL-21 protein (His tag C-Terminus) (AB235875)
15% SDS-PAGE analysis of 3 μg ab235875.
18-28 kDa (Reducing conditions).
보완 제품
Reactivity 정보
서열 정보
특성 및 보관 정보
제형
Purification 테크닉
배송 시 보관 조건
적절한 단기 보관 기간
적절한 단기 보관 조건
적절한 장기 보관 조건
분주 정보
보관 정보
일반 정보
기능
Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells (PubMed : 11081504, PubMed : 15178704). During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation (By similarity).
서열 유사성
Belongs to the IL-15/IL-21 family.
타겟 정보
Product promise
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