Recombinant Human IL-29/IFN-lambda 1 Protein is a Human Full Length protein, in the 20 to 200 aa range, expressed in HEK 293 cells, with >95%, <0.005 EU/µg endotoxin level, suitable for HPLC, Mass Spec.
대체 명칭 보기
IL29, ZCYTO21, IFNL1, Interferon lambda-1, IFN-lambda-1, Cytokine Zcyto21, Interleukin-29, IL-29
- Mass Spec
Supplier Data
Mass Spectrometry - Recombinant Human IL-29/IFN-lambda 1 Protein (AB315876)
Mass spectrometry MS/MS analysis of ab315876
- HPLC
Supplier Data
HPLC - Recombinant Human IL-29/IFN-lambda 1 Protein (AB315876)
HPLC analysis of ab315876
Reactivity 정보
서열 정보
특성 및 보관 정보
제형
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일반 정보
기능
Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets : is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
서열 유사성
Belongs to the type-III (or lambda) interferon family.
타겟 정보
Product promise
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