Recombinant human IL-31 protein (Active)
- Bioactive
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Recombinant human IL-31 protein (Active) is a Human Full Length protein, in the 24 to 164 aa range, expressed in Escherichia coli, with >95%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE, FuncS.
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Interleukin-31, IL-31, IL31
- FuncS
Supplier Data
Functional Studies - Recombinant human IL-31 protein (Active) (AB242434)
ab242434 induced activation of STAT3 in U-87 MG (human glioblastoma-astrocytoma epithelial cell line) cells.
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일반 정보
기능
Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR (PubMed : 15184896). May function in skin immunity (PubMed : 15184896). Enhances myeloid progenitor cell survival in vitro (By similarity). Induces RETNLA and serum amyloid A protein expression in macrophages (By similarity).
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