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AB288525

Recombinant Human IL-34 protein (Active)

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Recombinant Human IL-34 protein (Active) is a Human Full Length protein, in the 21 to 242 aa range, expressed in HEK 293 cells, with >95%, <0.005 EU/µg endotoxin level, suitable for SDS-PAGE, FuncS, Mass Spec, HPLC, Cell Culture.

대체 명칭 보기

C16orf77, IL34, Interleukin-34, IL-34

4 이미지
Mass Spectrometry - Recombinant Human IL-34 protein (Active) (AB288525)
  • Mass Spec

Supplier Data

Mass Spectrometry - Recombinant Human IL-34 protein (Active) (AB288525)

ESI TOF analysis of ab288525.

Predicted MW is 25289.0 Da (+/- 10 Da by ESI TOF). Observed MW is25290.13

Functional Studies - Recombinant Human IL-34 protein (Active) (AB288525)
  • FuncS

Supplier Data

Functional Studies - Recombinant Human IL-34 protein (Active) (AB288525)

Fully biologically active determined by dose dependent proliferation of PBMCs cells. ED50 is ≤2.082 ng/ml, corresponding to a specific activity of 4.8 x 105 units/mg.

HPLC - Recombinant Human IL-34 protein (Active) (AB288525)
  • HPLC

Supplier Data

HPLC - Recombinant Human IL-34 protein (Active) (AB288525)

HPLC analysis of ab288525.

SDS-PAGE - Recombinant Human IL-34 protein (Active) (AB288525)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human IL-34 protein (Active) (AB288525)

SDS-PAGE analysis of ab288525.

주요 정보

Purity

>95% SDS-PAGE

Purity by HPLC =95%

Endotoxin 레벨

<0.005 EU/µg

발현 시스템

HEK 293 cells

Tags

Tag free

Applications

HPLC, Mass Spec, FuncS, Cell Culture, SDS-PAGE

applications

Biologically active

Yes

Biological activity

Fully biologically active determined by dose dependent proliferation of PBMCs cells. ED50 is ≤2.082 ng/ml, corresponding to a specific activity of 4.8 x 105 units/mg.

Accession

Animal free

Yes

Carrier free

No

Species

Human

Reconstitution

Reconstitute in PBS

보관 버퍼

pH: 7.4 Constituents: 10.26% Trehalose, 0.727% Dibasic monohydrogen potassium phosphate, 0.248% Potassium phosphate monobasic

storage-buffer

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "HPLC": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Cell Culture": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

서열 정보

[{"linker":null,"sequence":"NEPLEMWPLTQNEECTVTGFLRDKLQYRSRLQYMKHYFPINYKISVPYEGVFRIANVTRLQRAQVSERELRYLWVLVSLSATESVQDVLLEGHPSWKYLQEVETLLLNVQQGLTDVEVSPKVESVLSLLNAPGPNLKLVRPKALLDNCFRVMELLYCSCCKQSSVLNWQDCEVPSPQSCSPEPSLQYAATQLYPPPPWSPSSPPHSTGSVRPVRAQGEGLLP","proteinLength":"Full Length","predictedMolecularWeight":"25.29 kDa","actualMolecularWeight":"25.9 kDa","aminoAcidEnd":242,"aminoAcidStart":21,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"Q6ZMJ4","tags":[]}]

특성 및 보관 정보

제형
Lyophilized
배송 시 보관 조건
Ambient - Can Ship with Ice
적절한 단기 보관 조건
Ambient
적절한 장기 보관 조건
Ambient
True

일반 정보

기능

Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.

서열 유사성

Belongs to the IL-34 family.

제품 프로토콜

타겟 정보

Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.
See full target information IL34

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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