Recombinant Human IL-34 protein (Active)
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Recombinant Human IL-34 protein (Active) is a Human Full Length protein, in the 21 to 242 aa range, expressed in HEK 293 cells, with >95%, <0.005 EU/µg endotoxin level, suitable for SDS-PAGE, FuncS, Mass Spec, HPLC, Cell Culture.
대체 명칭 보기
C16orf77, IL34, Interleukin-34, IL-34
- Mass Spec
Supplier Data
Mass Spectrometry - Recombinant Human IL-34 protein (Active) (AB288525)
ESI TOF analysis of ab288525.
Predicted MW is 25289.0 Da (+/- 10 Da by ESI TOF). Observed MW is25290.13
- FuncS
Supplier Data
Functional Studies - Recombinant Human IL-34 protein (Active) (AB288525)
Fully biologically active determined by dose dependent proliferation of PBMCs cells. ED50 is ≤2.082 ng/ml, corresponding to a specific activity of 4.8 x 105 units/mg.
- HPLC
Supplier Data
HPLC - Recombinant Human IL-34 protein (Active) (AB288525)
HPLC analysis of ab288525.
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human IL-34 protein (Active) (AB288525)
SDS-PAGE analysis of ab288525.
Reactivity 정보
서열 정보
특성 및 보관 정보
제형
배송 시 보관 조건
적절한 단기 보관 조건
적절한 장기 보관 조건
일반 정보
기능
Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.
서열 유사성
Belongs to the IL-34 family.
타겟 정보
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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