Recombinant Human ITIH5 protein (Tagged) is a Human Fragment protein, in the 35 to 161 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE.
대체 명칭 보기
KIAA1953, PP14776, UNQ311/PRO354, ITIH5, Inter-alpha-trypsin inhibitor heavy chain H5, ITI heavy chain H5, ITI-HC5, Inter-alpha-inhibitor heavy chain 5
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human ITIH5 protein (Tagged) (AB238235)
(Tris-Glycine gel) Discontinuous DSD-PAGE (reduced) with 5% enrichment gel and 15% separation gel analysis of ab238235.
보완 제품
Reactivity 정보
서열 정보
특성 및 보관 정보
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보관 정보
추가 정보
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
ITIH5 plays a role in extracellular matrix stabilization and tissue homeostasis. This protein participates in forming a protein complex with other inter-alpha-trypsin inhibitors which contributes to its functional capacity. ITIH5 shows importance in processes like cellular senescence and maintaining tissue integrity making it a relevant target in the context of cellular and systemic homeostasis.
Pathways
Several biological processes incorporate ITIH5 particularly those related to matrix remodeling and inflammation. One significant pathway involves the hyaluronan biosynthesis where ITIH5 interacts with proteins like TSG-6 facilitating the matrix assembly and stability. Another relevant interaction includes its association with matrix metalloproteinases mediating tissue remodeling during wound healing and inflammatory responses.
일반 정보
기능
May act as a tumor suppressor.
서열 유사성
Belongs to the ITIH family.
Product promise
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