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AB271567

Recombinant human KDM5B / PLU1 / Jarid1B protein (Active) (DDDDK N-Terminus + Avi tag N-Terminus)

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Recombinant human KDM5B / PLU1 / Jarid1B protein (Active) (DDDDK N-Terminus + Avi tag N-Terminus) is a Human Full Length protein, in the 2 to 1544 aa range, expressed in Baculovirus infected Sf9 cells, with >75%, suitable for SDS-PAGE, FuncS.

대체 명칭 보기

JARID1B, PLU1, RBBP2H1, KDM5B, Lysine-specific demethylase 5B, Cancer/testis antigen 31, Histone demethylase JARID1B, Jumonji/ARID domain-containing protein 1B, PLU-1, Retinoblastoma-binding protein 2 homolog 1, [histone H3]-trimethyl-L-lysine(4) demethylase 5B, CT31, RBP2-H1

2 이미지
Functional Studies - Recombinant human KDM5B / PLU1 / Jarid1B protein (Active) (DDDDK N-Terminus + Avi tag N-Terminus) (AB271567)
  • FuncS

Supplier Data

Functional Studies - Recombinant human KDM5B / PLU1 / Jarid1B protein (Active) (DDDDK N-Terminus + Avi tag N-Terminus) (AB271567)

Specific activity of ab271567.

SDS-PAGE - Recombinant human KDM5B / PLU1 / Jarid1B protein (Active) (DDDDK N-Terminus + Avi tag N-Terminus) (AB271567)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant human KDM5B / PLU1 / Jarid1B protein (Active) (DDDDK N-Terminus + Avi tag N-Terminus) (AB271567)

SDS-PAGE analysis of 2.3 μg ab271567.

주요 정보

Purity

>75% SDS-PAGE

Affinity purified.

발현 시스템

Baculovirus infected Sf9 cells

Tags

DDDDK tag N-Terminus Avi tag N-Terminus

Applications

SDS-PAGE, FuncS

applications

Biologically active

Yes

Biological activity

Specific Activity: 0.11 pmol/min/μg.

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 8 Constituents: 20% Glycerol (glycerin, glycerine), 0.64% Sodium chloride, 0.63% Tris HCl, 0.04% Sorbitan monolaurate, ethoxylated, 0.02% Potassium chloride, 0.01% TCEP HCl

storage-buffer

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보완 제품

Reagents, Controls & Accessories

AB313995

Prestained Protein Ladder - Mid-range molecular weight (15 - 170 kDa)

SDS-PAGE - Prestained Protein Ladder - Mid-range molecular weight (15 - 170 kDa) (AB313995)

  • 0
  • 0
Proteins & Peptides

AB125608

Recombinant Human KDM5C / Jarid1C / SMCX protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human KDM5C / Jarid1C / SMCX protein (AB125608)

  • 0
  • 0
Proteins & Peptides

AB271566

Recombinant human KDM5A / Jarid1A / RBBP2 protein (Active) (His N-Term + Avi N-Term + DDDDK C-Term)

Functional Studies - Recombinant human KDM5A / Jarid1A / RBBP2 protein (Active) (His N-Term + Avi N-Term + DDDDK C-Term) (AB271566)

  • 0
  • 0
Primary Antibodies

AB181089

Anti-KDM5B / PLU1 / Jarid1B antibody [EPR12704]

RabMAb|Recombinant|KO Validated

Western blot - Anti-KDM5B / PLU1 / Jarid1B antibody [EPR12704] (AB181089)

  • 5
  • 3
Primary Antibodies

AB4729

Anti-Histone H3 (acetyl K27) antibody - ChIP Grade

BOND RX™ Validated

ChIP - Anti-Histone H3 (acetyl K27) antibody - ChIP Grade (AB4729)

  • 5
  • 85
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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서열 정보

[{"linker":null,"sequence":"","proteinLength":"Full Length","predictedMolecularWeight":"179 kDa","actualMolecularWeight":null,"aminoAcidEnd":1544,"aminoAcidStart":2,"nature":"Recombinant","expressionSystem":null,"accessionNumber":"Q9UGL1","tags":[{"tag":"DDDDK","terminus":"N-Terminus"},{"tag":"Avi","terminus":"N-Terminus"}]}]
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification
배송 시 보관 조건
Dry Ice
적절한 단기 보관 조건
-80°C
적절한 장기 보관 조건
-80°C
보관 정보
Avoid freeze / thaw cycle
True
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일반 정보

기능

Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code (PubMed : 24952722, PubMed : 27214403, PubMed : 28262558). Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5 (PubMed : 24952722). In contrast, may act as a tumor suppressor for melanoma. Represses the CLOCK-BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity).

서열 유사성

Belongs to the JARID1 histone demethylase family.

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제품 프로토콜

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타겟 정보

Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code (PubMed : 24952722, PubMed : 27214403, PubMed : 28262558). Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5 (PubMed : 24952722). In contrast, may act as a tumor suppressor for melanoma. Represses the CLOCK-BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity).
See full target information KDM5B
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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