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AB127606

Recombinant Human KIAA0652/ATG13 protein (GST tag N-Terminus)

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Recombinant Human KIAA0652/ATG13 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 517 aa range, expressed in Escherichia coli, with >70%, suitable for SDS-PAGE, WB.

대체 명칭 보기

KIAA0652, ATG13, Autophagy-related protein 13

1 이미지
SDS-PAGE - Recombinant Human KIAA0652/ATG13 protein (AB127606)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human KIAA0652/ATG13 protein (AB127606)

SDS-PAGE analysis of ab127606.

주요 정보

Purity

>70% Densitometry

발현 시스템

Escherichia coli

Tags

GST tag N-Terminus

Applications

SDS-PAGE, WB

applications

Biologically active

No

Accession

Animal free

No

Carrier free

No

Species

Human

보관 버퍼

pH: 7.5 Constituents: 25% Glycerol (glycerin, glycerine), 0.79% Tris HCl, 0.31% Glutathione, 0.29% Sodium chloride, 0.004% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.003% EDTA, 0.002% PMSF

storage-buffer

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보완 제품

Primary Antibodies

AB201467

Anti-KIAA0652/ATG13 antibody [EPR19601]

RabMAb|Recombinant

Flow Cytometry (Intracellular) - Anti-KIAA0652/ATG13 antibody [EPR19601] (AB201467)

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Primary Antibodies

AB32370

Anti-Bcl-XL antibody [E18]

20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Bcl-XL antibody [E18] (AB32370)

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Proteins & Peptides

AB139254

Recombinant Human CD3 zeta protein (His tag N-Terminus)

SDS-PAGE - Recombinant Human CD3 zeta protein (His tag N-Terminus) (AB139254)

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Proteins & Peptides

AB104668

Recombinant Human hnRNP C1/C2 protein (His tag N-Terminus)

SDS-PAGE - Recombinant Human hnRNP C1/C2 protein (His tag N-Terminus) (AB104668)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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제품 세부 정보

This product was previously labelled as KIAA0652
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서열 정보

[{"linker":null,"sequence":"","proteinLength":"Full Length","predictedMolecularWeight":"96 kDa","actualMolecularWeight":null,"aminoAcidEnd":517,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":null,"accessionNumber":"O75143","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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특성 및 보관 정보

제형
Liquid
배송 시 보관 조건
Dry Ice
적절한 단기 보관 조건
-80°C
적절한 장기 보관 조건
-80°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
False
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일반 정보

기능

Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.

서열 유사성

Belongs to the ATG13 family. Metazoan subfamily.

Post-translational modifications

Phosphorylated by ULK1, ULK2 and mTOR. Phosphorylation status depends on nutrient-rich conditions; dephosphorylated during starvation or following treatment with rapamycin. ULK1-mediated phosphorylation of ATG13 at Ser-355 is required for efficient clearance of depolarized mitochondria.

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제품 프로토콜

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타겟 정보

Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
See full target information ATG13
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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