Recombinant Human Lingo1 protein (denatured) (His tag N-Terminus)
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Recombinant Human Lingo1 protein (denatured) (His tag N-Terminus) is a Human Fragment protein, in the 241 to 337 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE.
대체 명칭 보기
LERN1, LRRN6A, UNQ201/PRO227, LINGO1, Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1, Leucine-rich repeat and immunoglobulin domain-containing protein 1, Leucine-rich repeat neuronal protein 1, Leucine-rich repeat neuronal protein 6A
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human Lingo1 protein (denatured) (His tag N-Terminus) (AB202603)
15% SDS-PAGE analysis of 3 μg of ab202603.
Reactivity 정보
서열 정보
특성 및 보관 정보
제형
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분주 정보
보관 정보
일반 정보
기능
Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed : 14966521, PubMed : 15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed : 15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity).
Post-translational modifications
N-glycosylated. Contains predominantly high-mannose glycans.
타겟 정보
Product promise
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